V1RA7 Inhibitors
V1RA7 inhibitors constitute a distinct class of chemical compounds designed to specifically interact with the V1RA7 protein. This class is noted for its diverse structural elements, which include a range of organic molecules that have been meticulously designed to achieve high specificity and affinity for V1RA7. The chemical structures of V1RA7 inhibitors often feature a combination of aromatic rings, heterocyclic systems, and various functional groups that are strategically placed to facilitate effective binding to the protein. These inhibitors are characterized by their ability to fit into the protein's binding site with precision, often leveraging hydrogen bonds, hydrophobic interactions, and electrostatic forces to stabilize the inhibitor-protein complex.
The synthesis of V1RA7 inhibitors involves complex organic chemistry techniques, including multi-step synthetic routes and advanced methods such as combinatorial chemistry. Researchers use a variety of synthetic approaches to create these inhibitors, including the manipulation of molecular frameworks to optimize binding properties. Techniques like molecular modeling and high-throughput screening are employed to identify and refine compounds that demonstrate strong interactions with V1RA7. The iterative process of designing, synthesizing, and testing these inhibitors ensures that they possess the desired attributes for interacting with the target protein, making them important for understanding the biochemical roles and interactions of V1RA7 in various experimental settings.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Actinomycin D inhibits the expression of vomeronasal 1 receptor 47 by intercalating into DNA, preventing transcription initiation and elongation, thereby blocking the synthesis of mRNA. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
α-Amanitin inhibits the expression of vomeronasal 1 receptor 47 by binding to RNA polymerase II, blocking transcriptional elongation and leading to reduced mRNA levels. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Cycloheximide inhibits the expression of vomeronasal 1 receptor 47 by binding to the 60S ribosomal subunit, blocking peptide bond formation during translation, resulting in decreased protein synthesis. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
Rifampicin inhibits the expression of vomeronasal 1 receptor 47 by binding to bacterial RNA polymerase, blocking transcription initiation and indirectly reducing mRNA levels. | ||||||
Thiolutin | 87-11-6 | sc-200387 sc-200387A | 1 mg 5 mg | $101.00 $406.00 | 1 | |
Thiolutin inhibits the expression of vomeronasal 1 receptor 47 by binding to RNA polymerase and blocking transcriptional elongation, resulting in reduced mRNA synthesis and protein expression. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $101.00 | 5 | |
Cordycepin inhibits the expression of vomeronasal 1 receptor 47 by being incorporated into mRNA during transcription, leading to premature termination of transcription and reduced mRNA levels. | ||||||
Puromycin dihydrochloride | 58-58-2 | sc-108071 sc-108071B sc-108071C sc-108071A | 25 mg 250 mg 1 g 50 mg | $42.00 $214.00 $832.00 $66.00 | 394 | |
Puromycin inhibits the expression of vomeronasal 1 receptor 47 by incorporating into growing polypeptide chains during translation, causing premature termination and synthesis of truncated proteins. | ||||||
Siomycin A | 12656-09-6 | sc-202339 sc-202339-CW sc-202339A sc-202339B | 500 µg 500 µg 2.5 mg 25 mg | $450.00 $500.00 $1350.00 $10404.00 | 4 | |
Siomycin A inhibits the expression of vomeronasal 1 receptor 47 by binding to RNA polymerase and preventing the formation of the transcription complex, leading to transcriptional arrest and reduced mRNA synthesis. | ||||||
Homoharringtonine | 26833-87-4 | sc-202652 sc-202652A sc-202652B | 1 mg 5 mg 10 mg | $52.00 $125.00 $182.00 | 11 | |
Homoharringtonine inhibits the expression of vomeronasal 1 receptor 47 by binding to the ribosome and inhibiting protein synthesis, resulting in decreased levels of the target protein. | ||||||