V1RA1 Activators
Chemical activators of V1RA1 initiate a series of intracellular events through the engagement of G protein-coupled receptors (GPCRs). Epinephrine and norepinephrine, upon binding to adrenergic receptors, can activate V1RA1 by inducing a conformational change that translates into functional activity within cellular signaling. Similarly, isoproterenol, acting on beta-adrenergic receptors, can activate V1RA1 and engage it in the subsequent signaling cascades. Dopamine, with its specific dopamine receptors within the GPCR family, can also lead to the activation of V1RA1, underlining the broad scope of GPCR-mediated V1RA1 activation.
Further expanding the landscape of V1RA1 activators, histamine, by interacting with histamine receptors, can trigger signaling pathways that involve V1RA1 activation. Acetylcholine, by engaging muscarinic acetylcholine receptors, and serotonin, through serotonin receptors, similarly can activate V1RA1 as part of the complex signaling networks governed by these neurotransmitters. Angiotensin II, oxytocin, and vasopressin, each by binding to their respective receptors, can also result in the activation of V1RA1, underscoring the diverse physiological contexts in which V1RA1 can be activated. Finally, adenosine and glucagon, through their respective GPCR interactions, can facilitate the activation of V1RA1, further illustrating the extensive range of chemical signals that utilize GPCR pathways to modulate the function of V1RA1.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $40.00 $102.00 $197.00 $1739.00 $16325.00 | ||
Epinephrine activates adrenergic receptors which are G protein-coupled receptors (GPCRs) that V1RA1 belongs to. Activation of these receptors can lead to a conformational change in V1RA1, causing it to become functionally active as part of the cellular response to adrenergic stimulation. | ||||||
L-Noradrenaline | 51-41-2 | sc-357366 sc-357366A | 1 g 5 g | $320.00 $475.00 | 3 | |
Norepinephrine, similar to epinephrine, targets adrenergic receptors and can induce activation of V1RA1 through the same GPCR-mediated mechanism, leading to its functional activation in cellular signaling processes. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $92.00 $277.00 $969.00 | 7 | |
Histamine activates histamine receptors, which are GPCRs. This activation can lead to downstream intracellular signaling cascades that involve the activation of V1RA1 through G protein signaling pathways. | ||||||
3-(2-Aminoethyl)-1H-indol-5-ol | 50-67-9 | sc-298707 | 1 g | $520.00 | 3 | |
Serotonin binds to serotonin receptors, another class of GPCRs. The activation of these receptors can lead to the functional activation of V1RA1 through second messenger systems and signaling pathways linked to these receptors. | ||||||
Angiotensin II, Human | 4474-91-3 | sc-363643 sc-363643A sc-363643B sc-363643C | 1 mg 5 mg 25 mg 100 mg | $50.00 $75.00 $260.00 $505.00 | 3 | |
Angiotensin II interacts with angiotensin receptors which are part of the GPCR family. This interaction could activate V1RA1 as it might be involved in the angiotensin receptor signaling pathway. | ||||||
Oxytocin acetate salt | 50-56-6 | sc-279938 sc-279938A sc-279938B sc-279938C sc-279938D sc-279938E | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $59.00 $176.00 $330.00 $650.00 $950.00 $1800.00 | 4 | |
Oxytocin binds to oxytocin receptors, causing activation of GPCRs and potentially leading to the activation of V1RA1 due to the interconnected signaling pathways of these receptors. | ||||||
Vasopressin | 11000-17-2 | sc-356188 sc-356188A | 5 mg 25 mg | $255.00 $1020.00 | 1 | |
Vasopressin interacts with vasopressin receptors, which are GPCRs. This interaction could lead to the functional activation of V1RA1 as it is potentially involved in the signaling pathways activated by these receptors. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $33.00 $47.00 $294.00 $561.00 $1020.00 $2550.00 $4590.00 | 1 | |
Adenosine activates adenosine receptors, which are GPCRs, and can result in the activation of V1RA1 due to the shared signaling pathways between adenosine receptors and V1RA1. | ||||||