UBN-2 Inhibitors
UBN-2 Inhibitors represent a diverse array of chemical compounds designed to modulate the function of the UBN-2 protein, a molecule with known significance in various cellular processes. The variety of mechanisms by which these compounds exert their inhibitory effects on UBN-2 is vast, reflecting the complexity of cellular networks and the myriad ways in which a single protein can be influenced. Some inhibitors in this class specifically target enzymatic pathways, modifying the protein's interactions within the cellular environment. For instance, MG132 disrupts proteasomal activity, thereby possibly altering the typical function or interaction network of proteins like UBN-2. Others, such as Trichostatin A, affect chromatin structure, which can in turn disrupt UBN-2 interactions within the nucleus.
The broad spectrum of UBN-2 Inhibitors also encompasses compounds like Staurosporine, which inhibits kinases and thereby affects phosphorylation events. This highlights for these inhibitors to impact phosphorylation-mediated regulation of UBN-2 or its partner proteins. In a different vein, compounds like Curcumin could impede UBN-2's role in nucleosome assembly, given its inhibitory effect on nucleosome assembly proteins. Similarly, DNA intercalators, like Doxorubicin, might hinder UBN-2's interaction with DNA or DNA-associated proteins by inducing changes in DNA structure.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
MG132 hampers proteasomal activity, which might stabilize proteins interacting with UBN-2, thus altering its normal function or interaction network. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
As a histone deacetylase inhibitor, Trichostatin A modifies chromatin structure. This could disrupt UBN-2's potential interactions within the nucleus. | ||||||
W-7 | 61714-27-0 | sc-201501 sc-201501A sc-201501B | 50 mg 100 mg 1 g | $166.00 $306.00 $1675.00 | 18 | |
W-7's inhibition of calmodulin may disrupt calcium-signaling pathways where UBN-2 functions, limiting its cellular activity. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $176.00 $426.00 | 43 | |
Doxorubicin's DNA intercalation might hinder UBN-2's interaction with DNA or DNA-associated proteins by altering the DNA structure. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
By inhibiting kinases, Staurosporine affects phosphorylation events, which may inhibit any phosphorylation-mediated regulation of UBN-2 or its interacting partners. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin's potential inhibition of nucleosome assembly proteins might impede any UBN-2 role in nucleosome assembly or related activities. | ||||||
Olaparib | 763113-22-0 | sc-302017 sc-302017A sc-302017B | 250 mg 500 mg 1 g | $210.00 $305.00 $495.00 | 10 | |
Olaparib inhibits poly (ADP-ribose) polymerases. If UBN-2 is associated with DNA repair processes influenced by these enzymes, its function could be hampered. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
By inhibiting RNA polymerase II, α-Amanitin might prevent any UBN-2 involved transcription events or related interactions. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
As a DNA methyltransferase inhibitor, 5-Azacytidine could affect DNA methylation patterns, potentially affecting UBN-2 functions linked to DNA methylation. | ||||||
Ciprofloxacin | 85721-33-1 | sc-217900 | 1 g | $43.00 | 8 | |
Ciprofloxacin's inhibition of DNA gyrase alters DNA supercoiling. If UBN-2 interacts with specific DNA structures, this change might impede its function. | ||||||