Trav9n-3 Inhibitors
TRAV9n-3 inhibitors are a class of chemical compounds designed to target and inhibit the TRAV9n-3 gene segment, which encodes a variable region of the T-cell receptor alpha chain in mice. This receptor region plays a crucial role in recognizing antigens and initiating immune responses. By inhibiting TRAV9n-3, these compounds interfere with the formation of specific T-cell receptors, potentially affecting the ability of T cells to recognize and respond to antigens. This inhibition can lead to altered immune signaling and reduced activity in pathways dependent on T-cell receptor activation.
Chemically, TRAV9n-3 inhibitors are designed to block the binding or expression of this specific variable segment, preventing its proper integration into the T-cell receptor complex. Researchers focus on the structure of the variable region to ensure these inhibitors are selective for TRAV9n-3 without affecting other similar T-cell receptor regions. Studying these inhibitors helps illuminate the specific roles TRAV9n-3 plays in immune system regulation and antigen recognition, providing deeper insight into how individual T-cell receptor segments contribute to immune diversity and function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG inhibits T cell receptor alpha variable 9N-3 expression by modulating NF-κB activity, a key transcription factor in T cell activation, thereby reducing inflammatory response. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane inhibits T cell receptor alpha variable 9N-3 expression by suppressing NF-κB activation, which regulates T cell differentiation and cytokine production. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein inhibits T cell receptor alpha variable 9N-3 expression by blocking NF-κB activation, thereby reducing T cell proliferation and inflammatory cytokine production. | ||||||
Ursolic Acid | 77-52-1 | sc-200383 sc-200383A | 50 mg 250 mg | $55.00 $176.00 | 8 | |
Ursolic acid inhibits T cell receptor alpha variable 9N-3 expression by suppressing NF-κB activation and reducing the production of pro-inflammatory cytokines by T cells. | ||||||
Piceatannol | 10083-24-6 | sc-200610 sc-200610A sc-200610B | 1 mg 5 mg 25 mg | $50.00 $70.00 $195.00 | 11 | |
Piceatannol inhibits T cell receptor alpha variable 9N-3 expression by inhibiting NF-κB activation, thereby reducing T cell proliferation and pro-inflammatory cytokine production. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $26.00 $50.00 $99.00 $150.00 $1887.00 | 40 | |
Luteolin inhibits T cell receptor alpha variable 9N-3 expression by suppressing NF-κB activation and reducing the production of pro-inflammatory cytokines by T cells. | ||||||
Baicalin | 21967-41-9 | sc-204638 sc-204638A sc-204638B sc-204638C | 1 mg 25 mg 1 g 5 g | $55.00 $110.00 $220.00 $260.00 | 4 | |
Baicalin inhibits T cell receptor alpha variable 9N-3 expression by blocking NF-κB activation, thereby reducing T cell proliferation and pro-inflammatory cytokine production. | ||||||
Xanthohumol from hop (Humulus lupulus) | 6754-58-1 | sc-301982 | 5 mg | $354.00 | 1 | |
Xanthohumol inhibits T cell receptor alpha variable 9N-3 expression by suppressing NF-κB activation and reducing the production of pro-inflammatory cytokines by T cells. | ||||||
Salvianolic Acid B | 121521-90-2 | sc-212911B sc-212911 sc-212911A sc-212911C | 5 mg 10 mg 25 mg 100 mg | $235.00 $306.00 $551.00 $1837.00 | 6 | |
Salvianolic acid B inhibits T cell receptor alpha variable 9N-3 expression by blocking NF-κB activation, thereby reducing T cell proliferation and inflammatory cytokine production. | ||||||
Resorcinol | 108-46-3 | sc-203371 sc-203371A sc-203371B | 100 g 500 g 25 g | $56.00 $205.00 $30.00 | 1 | |
Resorcinol inhibits T cell receptor alpha variable 9N-3 expression by suppressing NF-κB activation and reducing the production of pro-inflammatory cytokines by T cells. | ||||||