TRAF7 activators comprise a range of chemicals that can indirectly modulate the activity of TRAF7 by influencing the signaling pathways that TRAF7 is involved in, particularly the NF-kappaB and JNK pathways. These chemicals primarily include inhibitors of NF-kappaB activation and modulators of the JNK pathway. NF-kappaB inhibitors work by inhibiting the activation of NF-kappaB, a downstream pathway of TRAF7, thereby potentially influencing TRAF7 activity.
On the other hand, activaors that modulate the JNK pathway may also influence TRAF7 activity indirectly. TRAF7 activators work by influencing the TRPV1 ion channel, leading to increased intracellular calcium levels that can modulate both NF-kappaB and JNK pathways, thereby potentially influencing TRAF7.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
IKK-2 Inhibitor IV | 507475-17-4 | sc-203083 | 500 µg | $133.00 | 12 | |
IKK-2 Inhibitor IV is an inhibitor of IKK-2, which is involved in the NF-kappaB pathway. By inhibiting IKK-2, TPCA-1 can modulate the activity of NF-kappaB, potentially influencing TRAF7 which is upstream of this pathway. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
BAY 11-7082 is an inhibitor of NF-kappaB activation. It works by inhibiting IκBα phosphorylation, potentially influencing TRAF7 upstream. | ||||||
JNK Inhibitor XVI | 1410880-22-6 | sc-364745 | 10 mg | $357.00 | 5 | |
JNK Inhibitor XVI is a JNK inhibitor that can modulate the JNK pathway, potentially influencing TRAF7, which is an upstream regulator of this pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor that can modulate the JNK pathway, potentially influencing TRAF7, which is an upstream regulator of this pathway. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Anisomycin is a potent activator of the JNK pathway. By activating JNK, it can potentially influence TRAF7 upstream. | ||||||
Parthenolide | 20554-84-1 | sc-3523 sc-3523A | 50 mg 250 mg | $81.00 $306.00 | 32 | |
Parthenolide is a sesquiterpene lactone that inhibits NF-kappaB activation, potentially influencing TRAF7 upstream. | ||||||
Emodin | 518-82-1 | sc-202601 sc-202601A sc-202601B | 50 mg 250 mg 15 g | $105.00 $214.00 $6255.00 | 2 | |
Emodin is an anthraquinone that inhibits NF-kappaB activation, potentially influencing TRAF7 upstream. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin is a vanilloid that activates the TRPV1 ion channel, leading to increased intracellular calcium levels and potential modulation of NF-kappaB and JNK pathways, potentially influencing TRAF7. | ||||||
Oleuropein | 32619-42-4 | sc-286622 sc-286622A sc-286622B sc-286622C | 500 mg 1 g 10 g 100 g | $359.00 $530.00 $791.00 $6773.00 | 2 | |
Oleuropein is a secoiridoid that inhibits NF-kappaB activation, potentially influencing TRAF7 upstream. | ||||||