Date published: 2025-10-30

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Oleuropein (CAS 32619-42-4)

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Alternate Names:
Oleoeuropeine
Application:
Oleuropein is an antioxidant and immunomodulator in vitro that is a tyrosol ester derivative of elenolic acid (sc-497404) and phenolic glycoside found naturally olive oil
CAS Number:
32619-42-4
Molecular Weight:
540.51
Molecular Formula:
C25H32O13
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Oleuropein is a phenolic compound found in the leaves, fruit, and bark of the olive tree (Olea europaea). It works by inhibiting the activity of enzymes involved in inflammation and oxidative stress, as well as activating certain signaling pathways. In vitro research has shown that oleuropein has a wide range of biological activities, including anti-inflammatory, antimicrobial, anti-tumor, and potent antioxidant effects.


Oleuropein (CAS 32619-42-4) References

  1. Bioactive compounds from extra virgin olive oils: Correlation between phenolic content and oxidative stress cell protection.  |  Presti, G., et al. 2017. Biophys Chem. 230: 109-116. PMID: 28965785
  2. Protective effects of oleuropein against renal injury oxidative damage in alloxan-induced diabetic rats; a histological and biochemical study.  |  Ahmadvand, H., et al. 2017. J Nephropathol. 6: 204-209. PMID: 28975102
  3. Bioactivity of Olive Oil Phenols in Neuroprotection.  |  Angeloni, C., et al. 2017. Int J Mol Sci. 18: PMID: 29068387
  4. Evaluation of phenolic composition and antioxidant activity changes in olive flowers during development using HPLC/DAD and LC-MS/MS.  |  Rekik, O., et al. 2018. Electrophoresis. 39: 1663-1672. PMID: 29082534
  5. Oleuropein Is Responsible for the Major Anti-Inflammatory Effects of Olive Leaf Extract.  |  Qabaha, K., et al. 2018. J Med Food. 21: 302-305. PMID: 29099642
  6. Olive (Olea europaea L.) Biophenols: A Nutriceutical against Oxidative Stress in SH-SY5Y Cells.  |  Omar, SH., et al. 2017. Molecules. 22: PMID: 29109370
  7. Oleuropein protects intracerebral hemorrhage-induced disruption of blood-brain barrier through alleviation of oxidative stress.  |  Shi, J., et al. 2017. Pharmacol Rep. 69: 1206-1212. PMID: 29128801
  8. Anti-inflammatory Activity of Extra Virgin Olive Oil Polyphenols: Which Role in the Prevention and Treatment of Immune-Mediated Inflammatory Diseases?  |  Santangelo, C., et al. 2018. Endocr Metab Immune Disord Drug Targets. 18: 36-50. PMID: 29141574
  9. Effect of the composition of extra virgin olive oils on the differentiation and antioxidant capacities of twelve monovarietals.  |  Fuentes, E., et al. 2018. Food Chem. 243: 285-294. PMID: 29146340
  10. Synthesis and antioxidant evaluation of lipophilic oleuropein aglycone derivatives.  |  Nardi, M., et al. 2017. Food Funct. 8: 4684-4692. PMID: 29160876
  11. Modification of pomological characteristics and flavour components of fruits and virgin olive oil following wastewater irrigation and soil tillage.  |  Tekaya, M., et al. 2018. J Sci Food Agric. 98: 2942-2952. PMID: 29168201
  12. Oleuropein improves insulin resistance in skeletal muscle by promoting the translocation of GLUT4.  |  Fujiwara, Y., et al. 2017. J Clin Biochem Nutr. 61: 196-202. PMID: 29203961
  13. An effective HPLC-based approach for the evaluation of the content of total phenolic compounds transferred from olives to virgin olive oil during the olive milling process.  |  Cecchi, L., et al. 2018. J Sci Food Agric. 98: 3636-3643. PMID: 29250777
  14. Study of the combined effects of ripeness and production area on Bosana oil's quality.  |  Morrone, L., et al. 2018. Food Chem. 245: 1098-1104. PMID: 29287327
  15. Simple and efficient sustainable semi-synthesis of oleacein [2-(3,4-hydroxyphenyl) ethyl (3S,4E)-4-formyl-3-(2-oxoethyl)hex-4-enoate] as potential additive for edible oils.  |  Costanzo, P., et al. 2018. Food Chem. 245: 410-414. PMID: 29287389

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Oleuropein, 500 mg

sc-286622
500 mg
$352.00

Oleuropein, 1 g

sc-286622A
1 g
$520.00

Oleuropein, 10 g

sc-286622B
10 g
$775.00

Oleuropein, 100 g

sc-286622C
100 g
$6640.00