Date published: 2026-7-10

1-800-457-3801

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Topo CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. Topo gene silencers are available as Topo CRISPR/Cas9 Knockout plasmids and Topo Double Nickase Plasmids. Topo CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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Topo CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Topo IIβ CRISPR/Cas9 KO Plasmid (h)

sc-400773Gene Knockouth0
(0)

Topo IIα CRISPR/Cas9 KO Plasmid (h)

sc-400869Gene Knockouth0
(0)

Topo I CRISPR/Cas9 KO Plasmid (h)

sc-400965Gene Knockouth0
(0)

Topo IIIα CRISPR/Cas9 KO Plasmid (h)

sc-404439Gene Knockouth0
(0)

Topo IIIβ CRISPR/Cas9 KO Plasmid (h)

sc-406840Gene Knockouth0
(0)

Topo I CRISPR/Cas9 KO Plasmid (m)

sc-423468Gene Knockoutm0
(0)

Topo IIα CRISPR/Cas9 KO Plasmid (m)

sc-423469Gene Knockoutm0
(0)

Topo IIβ CRISPR/Cas9 KO Plasmid (m)

sc-423470Gene Knockoutm0
(0)

Topo IIIα CRISPR/Cas9 KO Plasmid (m)

sc-423471Gene Knockoutm0
(0)

Topo IIIβ CRISPR/Cas9 KO Plasmid (m)

sc-423472Gene Knockoutm0
(0)

Topo IIβ HDR Plasmid (h)

sc-400773-HDRHomology Directed Repairh0
(0)

Topo IIα HDR Plasmid (h)

sc-400869-HDRHomology Directed Repairh0
(0)

Topo I HDR Plasmid (h)

sc-400965-HDRHomology Directed Repairh0
(0)

Topo I HDR Plasmid (m)

sc-423468-HDRHomology Directed Repairm0
(0)

Topo IIα HDR Plasmid (m)

sc-423469-HDRHomology Directed Repairm0
(0)

Topo IIβ HDR Plasmid (m)

sc-423470-HDRHomology Directed Repairm0
(0)

Topo CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Topo IIβ Double Nickase Plasmid (h)

sc-400773-NICGene Knockouth0
(0)

Topo IIβ Double Nickase Plasmid (h2)

sc-400773-NIC-2Gene Knockouth0
(0)

Topo CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Topo IIβ CRISPR Activation Plasmid (h)

sc-400773-ACTGene Activationh0
(0)

Topo IIα CRISPR Activation Plasmid (h)

sc-400869-ACTGene Activationh0
(0)

Topo I CRISPR Activation Plasmid (h)

sc-400965-ACTGene Activationh0
(0)

Topo IIIα CRISPR Activation Plasmid (h)

sc-404439-ACTGene Activationh0
(0)

Topo IIα CRISPR Activation Plasmid (h2)

sc-400869-ACT-2Gene Activationh0
(0)