Tom6 Activators
Translocase of Outer Mitochondrial Membrane 6 (TOMM6) is a protein that, in humans, is encoded by the TOMM6 gene. It is part of the TOMM complex (translocase of the outer mitochondrial membrane), which is responsible for the recognition and translocation of nuclear-encoded proteins into the mitochondria.The TOMM complex is crucial for mitochondrial function, as it enables the import of proteins synthesized in the cytoplasm that are destined for the mitochondria. These proteins include those involved in oxidative phosphorylation, mitochondrial DNA maintenance, and other key mitochondrial functions.
As a component of the TOMM complex, TOMM6 helps facilitate this import process. While the specific role of TOMM6 within the complex isn't fully understood, it's likely that it contributes to the overall structure of the TOMM complex and/or the recognition and passage of proteins into the mitochondria.Disruptions in mitochondrial protein import can have serious consequences, as it can impair mitochondrial function and lead to a variety of mitochondrial diseases.In summary, TOMM6 is a component of the TOMM complex, which is essential for the import of proteins into the mitochondria. TOMM6 likely contributes to the structure and function of the TOMM complex, playing a role in maintaining mitochondrial function.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Metformin, primarily known for its role in glucose metabolism, might indirectly affect mitochondrial function and thereby influence TOMM6. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
Compounds that modulate reactive oxygen species (ROS) levels could impact mitochondrial dynamics, potentially affecting TOMM6. | ||||||
Mdivi-1 | 338967-87-6 | sc-215291 sc-215291B sc-215291A sc-215291C | 5 mg 10 mg 25 mg 50 mg | $66.00 $124.00 $246.00 $456.00 | 13 | |
Regulators of mitochondrial fission and fusion might influence the overall function of mitochondria, indirectly impacting TOMM6. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitors can affect cell growth and proliferation pathways, potentially intersecting with mitochondrial functions involving TOMM6. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
Activating AMP-activated protein kinase (AMPK) can influence energy metabolism and mitochondrial function, potentially impacting TOMM6. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Modulating mitochondrial permeability could indirectly impact the function of mitochondrial proteins like TOMM6. | ||||||
Dantrolene | 7261-97-4 | sc-500165 | 25 mg | $350.00 | 7 | |
Modulating intracellular calcium levels can affect mitochondrial function, potentially impacting TOMM6. | ||||||
(+)-α-Tocopherol | 59-02-9 | sc-214454 sc-214454A sc-214454B | 10 g 25 g 100 g | $42.00 $61.00 $138.00 | ||
Antioxidants, by reducing oxidative stress, might indirectly affect mitochondrial health and TOMM6 function. | ||||||
ABT-199 | 1257044-40-8 | sc-472284 sc-472284A sc-472284B sc-472284C sc-472284D | 1 mg 5 mg 10 mg 100 mg 3 g | $116.00 $330.00 $510.00 $816.00 $1632.00 | 10 | |
Compounds targeting Bcl-2 family proteins can influence mitochondrial apoptosis pathways, potentially impacting TOMM6. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $38.00 $58.00 $102.00 $202.00 | 8 | |
HSP90 inhibitors can disrupt protein folding and function, potentially affecting proteins involved in mitochondrial functions like TOMM6. | ||||||