TMEM88B Inhibitors
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a potent inhibitor of protein kinases. By inhibiting a broad range of kinases, it can disrupt downstream signaling pathways including those that might regulate the function or stability of TMEM88B indirectly, leading to a decrease in TMEM88B activity as signaling cascades are disrupted. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a specific inhibitor of phosphoinositide 3-kinases (PI3K). By inhibiting PI3K, it blocks the PI3K/AKT pathway, which could lead to a reduction in TMEM88B activity, since this pathway influences various cellular mechanisms that could intersect with TMEM88B's function. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is an inhibitor of MEK1/2, key enzymes in the MAPK/ERK pathway. By inhibiting this pathway, U0126 could diminish TMEM88B activity indirectly, as the MAPK/ERK pathway modulates numerous cellular processes that could involve TMEM88B. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY 294002 is another inhibitor of PI3K, and by blocking this kinase, it disrupts the PI3K/AKT signaling pathway. The inhibition of this pathway could lead to diminished TMEM88B activity due to the pathway's role in modulating various cellular processes that TMEM88B might be involved in. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD 98059 is an inhibitor of MEK, which is part of the MAPK pathway. By inhibiting MEK, PD98059 could lead to decreased TMEM88B activity indirectly by affecting the cellular processes modulated by the MAPK pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB 203580 is a specific inhibitor of p38 MAP kinase. The inhibition of p38 MAP kinase could lead to decreased activity of TMEM88B as the p38 MAPK pathway is involved in inflammatory responses and stress, which could be linked to TMEM88B's functional role. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
PP 2 is an Src family kinase inhibitor. By inhibiting Src kinases, PP2 could diminish TMEM88B activity by affecting the Src kinase signaling pathways that intersect with cellular processes TMEM88B is implicated in. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $65.00 $267.00 | 257 | |
SP600125 is an inhibitor of c-Jun N-terminal kinase (JNK). Inhibition of JNK could lead to decreased TMEM88B activity indirectly by affecting cellular processes linked to stress and cytokine signaling, which might intersect with TMEM88B's role. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is an inhibitor of mTOR, which is part of the PI3K/AKT pathway. By inhibiting mTOR, Rapamycin could diminish TMEM88B activity indirectly by affecting cellular growth and metabolism pathways that may involve TMEM88B. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $103.00 $237.00 | 36 | |
GF 109203X is a potent inhibitor of protein kinase C (PKC). By inhibiting PKC, this compound could lead to decreased TMEM88B activity by affecting signaling pathways that control various cellular processes, potentially including those involving TMEM88B. | ||||||