Date published: 2026-4-1

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TMEM222 Activators

The term TMEM222 Activators refers to a specific category of chemical compounds designed to modulate the activity of the TMEM222 gene or protein. TMEM222, also known as Transmembrane Protein 222, is a gene that encodes a protein embedded in the cell membrane, and its precise biological functions and regulatory mechanisms are subjects of ongoing research within the field of molecular biology and genetics. Activators within the TMEM222 Activators class typically consist of small molecules or chemical agents strategically engineered to interact with the TMEM222 gene or protein, with the aim of enhancing its expression or influencing its functional capabilities. These activators serve as valuable tools for researchers to manipulate TMEM222-related processes and explore its potential functions in the context of cellular membrane biology and cellular functions.

The mechanism of action for TMEM222 Activators may involve various aspects of gene regulation or protein function. These compounds could influence the binding of transcription factors to the promoter region of the TMEM222 gene, potentially increasing its transcriptional activity and leading to elevated TMEM222 gene expression levels. Alternatively, they might affect the post-translational modifications or interactions of the TMEM222 protein within the cell membrane, which can modulate its stability, function, or subcellular localization. Researchers and scientists employ TMEM222 Activators in molecular and cellular biology studies to investigate the role of TMEM222 in cellular membrane processes and potential implications in normal cellular physiology. By selectively modulating the gene's activity or protein function, researchers can gain insights into its functions, regulatory mechanisms, and potential involvement in various cellular pathways, contributing to a deeper understanding of the molecular processes involving TMEM222 and its significance in cellular biology. Overall, TMEM222 Activators provide valuable tools for exploring the functions and regulatory mechanisms of this transmembrane protein in the context of cellular membrane biology and cellular functions.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin, by elevating cAMP levels, could modulate cellular signaling pathways, potentially influencing TMEM222 expression as part of the cellular response to cAMP-mediated signals.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid, involved in cell differentiation and growth, might affect TMEM222 expression through its regulatory effects on gene expression via retinoic acid receptors.

Tunicamycin

11089-65-9sc-3506A
sc-3506
5 mg
10 mg
$172.00
$305.00
66
(3)

Tunicamycin, which induces ER stress by inhibiting N-linked glycosylation, could potentially upregulate TMEM222 as part of the unfolded protein response.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$136.00
$446.00
114
(2)

Thapsigargin, causing ER calcium depletion and stress, might increase TMEM222 expression as cells adapt to maintain calcium homeostasis and ER function.

Hydrogen Peroxide

7722-84-1sc-203336
sc-203336A
sc-203336B
100 ml
500 ml
3.8 L
$31.00
$61.00
$95.00
28
(1)

Hydrogen peroxide, inducing oxidative stress, could upregulate TMEM222 as part of the cellular antioxidant response mechanisms.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin, with its anti-inflammatory and antioxidant properties, might modulate TMEM222 expression as part of the cellular response to oxidative stress and inflammation.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$71.00
$163.00
$296.00
2
(1)

Vitamin D3 may modulate TMEM222 expression through the vitamin D receptor, potentially affecting cellular processes such as growth and differentiation.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

Sodium butyrate, an HDAC inhibitor, might enhance TMEM222 expression by altering chromatin structure and increasing gene accessibility for transcription.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Rapamycin, an mTOR inhibitor, could influence TMEM222 expression as part of cellular responses to altered growth conditions and autophagy.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

Dexamethasone, a glucocorticoid, could affect TMEM222 expression related to stress responses and inflammation through glucocorticoid receptor-mediated pathways.