The chemical class referred to as TIP47 inhibitors encompasses a diverse collection of organic compounds characterized by their distinctive ability to selectively modulate the activity of the Tail-Interacting Protein of 47 kDa (TIP47). TIP47 is a multifunctional protein intricately involved in intracellular processes, particularly those related to lipid metabolism and intracellular trafficking. TIP47 inhibitors exert their effects by interacting with specific binding sites associated with TIP47, thereby influencing the broader spectrum of cellular events mediated by this protein. These inhibitors are designed to exert a regulatory impact on TIP47-associated activities, potentially contributing to the modulation of intracellular dynamics.
The chemical structures of TIP47 inhibitors can vary significantly, and ongoing research endeavors aim to unravel the precise mechanisms through which they influence TIP47 function. As scientists continue to investigate the intricate role of TIP47 in various cellular pathways, TIP47 inhibitors represent a valuable tool for probing the complex web of interactions that underlie intracellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a natural product inhibitor that targets phosphoinositide 3-kinases (PI3Ks) and indirectly influences Tip47-mediated trafficking events. | ||||||
Exo1 | 461681-88-9 | sc-200752 sc-200752A | 10 mg 50 mg | $84.00 $297.00 | 4 | |
Exo1 is a specific inhibitor of Tip47 that has been used to study the protein's role in lipid droplet dynamics and lipid metabolism. | ||||||
CA-074 | 134448-10-5 | sc-202513 | 1 mg | $321.00 | ||
CA-074 is an inhibitor of cathepsin B, an enzyme that has been implicated in the regulation of Tip47-mediated processes. | ||||||
Imipramine hydrochloride | 113-52-0 | sc-207753 sc-207753B sc-207753A | 100 mg 1 g 5 g | $26.00 $45.00 $103.00 | 5 | |
Imipramine is a tricyclic antidepressant that has been reported to inhibit Tip47, potentially affecting its role in intracellular lipid trafficking. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Brefeldin A is a fungal metabolite that disrupts intracellular trafficking and has been employed to investigate Tip47-mediated processes. | ||||||