Date published: 2025-10-25

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TIGD3 Activators

TIGD3 activators are compounds that have the capacity to modulate the activity of the TIGD3 protein, either directly or indirectly. Given the paucity of direct activators for TIGD3, the majority of compounds in this class tend to exert their effects by impacting cellular pathways and processes that TIGD3 is involved in or responsive to.

The influence of antioxidants such as Acetylcysteine on oxidative stress pathways underscores the modulation of TIGD3 plays a role in cellular responses to oxidative conditions. Similarly, Dexamethasone's effect on anti-inflammatory responses brings to light the possible indirect modulation of TIGD3 its functions intersect with inflammation or stress pathways. The AMPK pathway, pivotal in energy homeostasis, offers another route for modulation. Compounds such as Metformin, AICAR, Dorsomorphin, and A-769662 that influence the AMPK pathway may indirectly modulate TIGD3 it interacts or is regulated by cellular energy processes. Retinoic acid's modulation of retinoid signaling pathways and the influence of 5-Azacytidine on DNA methylation emphasize the intricate network of cellular processes and how they can affect proteins like TIGD3. Finally, compounds like Sodium butyrate that impact histone modification highlight the significance of chromatin remodeling in influencing the function and activity of TIGD3. The breadth of these compounds and their diverse cellular targets accentuate the vast interplay of cellular pathways and how a single protein's activity, like TIGD3's, can be influenced in a multitude of ways. This broad perspective not only illuminates the intricacy of cellular networks but also stresses the importance of a multifaceted approach when considering protein modulation.

SEE ALSO...

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

N-Acetyl-L-cysteine

616-91-1sc-202232
sc-202232A
sc-202232C
sc-202232B
5 g
25 g
1 kg
100 g
$33.00
$73.00
$265.00
$112.00
34
(1)

Acetylcysteine is an antioxidant that can affect oxidative stress pathways. If TIGD3 is implicated in cellular responses to oxidative stress, its activity may be modulated by changes in this pathway induced by Acetylcysteine.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$76.00
$82.00
$367.00
36
(1)

Dexamethasone is a glucocorticoid affecting anti-inflammatory responses. If TIGD3 has roles in inflammation or stress response, dexamethasone's modulation of these pathways can influence TIGD3.

Metformin

657-24-9sc-507370
10 mg
$77.00
2
(0)

Metformin activates AMPK pathway which plays roles in energy homeostasis. If TIGD3 interacts or is regulated by energy homeostasis processes, Metformin can modulate its function.

AICAR

2627-69-2sc-200659
sc-200659A
sc-200659B
50 mg
250 mg
1 g
$60.00
$270.00
$350.00
48
(2)

AICAR is an AMPK activator, playing roles in energy sensing. TIGD3's activity could be influenced if it is associated with cellular energy sensing or metabolism modulated by AICAR.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Retinoic acid modulates retinoid signaling pathways. If TIGD3 has associations with retinoid-responsive elements or processes, its activity could be influenced by Retinoic acid.

BML-275

866405-64-3sc-200689
sc-200689A
5 mg
25 mg
$94.00
$348.00
69
(1)

Dorsomorphin is an AMPK inhibitor affecting energy homeostasis. By influencing the AMPK pathway, it could indirectly modulate TIGD3 if TIGD3 is associated with energy-dependent processes.

Zinc

7440-66-6sc-213177
100 g
$47.00
(0)

Zinc chloride can influence zinc finger protein functions. If TIGD3's function or stability is dependent on zinc or related interactions, ZnCl2 could modulate its activity.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

5-Azacytidine inhibits DNA methyltransferases affecting DNA methylation. If TIGD3 is associated with or responds to DNA methylation status, its activity could be modulated by 5-Azacytidine.

Rosiglitazone

122320-73-4sc-202795
sc-202795A
sc-202795C
sc-202795D
sc-202795B
25 mg
100 mg
500 mg
1 g
5 g
$118.00
$320.00
$622.00
$928.00
$1234.00
38
(1)

Rosiglitazone activates PPARγ pathways related to lipid metabolism. If TIGD3 has interactions in lipid-related processes, its function might be influenced by Rosiglitazone.

Troglitazone

97322-87-7sc-200904
sc-200904B
sc-200904A
5 mg
10 mg
25 mg
$108.00
$200.00
$426.00
9
(1)

Troglitazone, like Rosiglitazone, is a PPARγ agonist. If TIGD3 is involved in pathways modulated by PPARγ, its activity could be influenced by Troglitazone.