Tescalcin is a fascinating protein known for its intricate role in cellular processes. It's a calcium-binding protein, and as its name might suggest, its interactions with calcium ions are central to its function. Calcium, beyond being a crucial component of our bones, plays an integral role as a second messenger in cells, mediating a plethora of cellular responses. The finely-tuned regulation of intracellular calcium levels is imperative for maintaining cellular homeostasis. Tescalcin, by virtue of its calcium-binding properties, is implicated in several calcium-mediated signaling pathways, influencing various cellular functions like proliferation, differentiation, and migration. Its role isn't just passive; the binding of calcium to Tescalcin can induce conformational changes in the protein, potentially modulating its interactions with other cellular constituents.
Tescalcin inhibitors are molecules engineered to modulate the activity of Tescalcin. Given the pivotal role of Tescalcin in calcium-mediated cellular processes, its inhibition can have profound effects on cellular homeostasis. These inhibitors might operate in several ways. Some might obstruct the calcium-binding sites of Tescalcin, preventing it from interacting with calcium ions. Others might interact with the protein in a manner that induces structural changes, rendering it inactive or altering its normal function. Yet another class might impede its synthesis or its stability within the cellular environment. The design and study of Tescalcin inhibitors provide invaluable insights into the protein's structure-function relationship, its interactions with calcium, and its broader role in the intricate ballet of cellular signaling and homeostasis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $449.00 | 61 | |
Intracellular calcium chelator. By affecting calcium signaling, might influence Tescalcin expression. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
SERCA pump inhibitor, increases cytosolic calcium. Could indirectly affect Tescalcin levels. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $58.00 $170.00 | 15 | |
Calcium channel blocker. By modulating calcium influx, might influence Tescalcin levels. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
MEK inhibitor, if Tescalcin expression is downstream of MEK signaling, this could have an effect. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
p38 MAPK inhibitor; if Tescalcin is regulated by p38 MAPK pathway, its levels might be affected. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $178.00 | 25 | |
CaMKII inhibitor; by modulating calcium-dependent signaling, could indirectly affect Tescalcin expression. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Calcineurin inhibitor; if Tescalcin expression is linked to calcineurin, this could have an effect. | ||||||
FK-506 | 104987-11-3 | sc-24649 sc-24649A | 5 mg 10 mg | $76.00 $148.00 | 9 | |
Another calcineurin inhibitor; might influence Tescalcin if its expression is regulated by calcineurin. | ||||||
Dantrolene | 7261-97-4 | sc-500165 | 25 mg | $350.00 | 7 | |
RyR inhibitor affecting calcium release from the ER, might have an indirect effect on Tescalcin. | ||||||
Carbachol | 51-83-2 | sc-202092 sc-202092A sc-202092C sc-202092D sc-202092B sc-202092E | 1 g 10 g 25 g 50 g 100 g 250 g | $120.00 $275.00 $380.00 $670.00 $1400.00 $3000.00 | 12 | |
Muscarinic receptor agonist, affects calcium signaling which might indirectly influence Tescalcin expression. | ||||||