Tenascin Inhibitors
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cilengitide | 188968-51-6 | sc-507335 | 5 mg | $215.00 | ||
Cilengitide targets integrins αvβ3 and αvβ5, which are known to interact with Tenascin-C. By blocking these integrins, Cilengitide can inhibit Tenascin-C-mediated cell adhesion and migration, which are critical functions of Tenascin-C. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Taxol binds to and stabilizes microtubules, preventing their disassembly. Since Tenascin-C is involved in cell movement and cytoskeletal organization, Taxol′s action can disrupt the dynamic microtubule structures necessary for Tenascin-C′s function. | ||||||
NSC 23766 | 733767-34-5 | sc-204823 sc-204823A | 10 mg 50 mg | $151.00 $609.00 | 75 | |
NSC 23766 inhibits Rac1, a GTPase involved in cytoskeletal organization. As Tenascin-C functions are associated with cytoskeletal changes during cell movement, inhibiting Rac1 can disrupt the processes where Tenascin-C is functionally involved. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 inhibits PI3K, a kinase involved in intracellular signaling pathways. Since Tenascin-C can be involved in signaling pathways that regulate cell survival and motility, inhibiting PI3K can lead to the functional inhibition of Tenascin-C. | ||||||
AG-490 | 133550-30-8 | sc-202046C sc-202046A sc-202046B sc-202046 | 5 mg 50 mg 25 mg 10 mg | $84.00 $329.00 $223.00 $87.00 | 35 | |
AG-490 is a tyrosine kinase inhibitor that can inhibit JAK/STAT signaling. Tenascin-C can interact with signaling pathways that modulate cellular behavior; hence, inhibiting JAK/STAT signaling can lead to the functional inhibition of Tenascin-C. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 inhibits JNK, which is part of the signaling pathways that affect cell structure and motility. By inhibiting JNK, SP600125 can disrupt cellular functions that are modulated by Tenascin-C, leading to its functional inhibition. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 inhibits MEK, which is upstream of ERK in the MAPK signaling pathway. Tenascin-C is implicated in regulating cell behavior through MAPK signaling. Inhibiting MEK can therefore disrupt these signaling events, leading to the functional inhibition of Tenascin-C. | ||||||