TEF-4 inhibitors constitute a diverse class of chemical compounds designed to modulate the activity of TEF-4, a transcription factor involved in cellular processes such as gene expression, cell growth, and metabolism. While no direct inhibitors have been identified, several chemicals targeting key signaling pathways associated with TEF-4 provide potential avenues for indirect modulation. AZD8055, Rapamycin, PP242, and Torin 1 are inhibitors of the mTOR kinase, offering indirect modulation of TEF-4 by impacting downstream signaling cascades related to cellular growth, metabolism, and protein synthesis. These compounds provide valuable tools to explore the regulatory roles of mTOR in TEF-4-mediated cellular processes.
LY294002 and Wortmannin are PI3K inhibitors that may influence TEF-4 through the PI3K/AKT signaling pathway. By inhibiting PI3K, these compounds can affect downstream signaling events intersecting with TEF-4-related pathways, potentially influencing the expression or activity of TEF-4 and offering insights into the regulatory roles of PI3K in TEF-4-mediated cellular processes. BEZ235, Akt Inhibitor VIII, SC79, MK-2206, GSK690693, and BKM120 target the PI3K/AKT signaling pathway, providing potential avenues for indirect modulation of TEF-4. These compounds may impact downstream events associated with TEF-4, shedding light on the intricate regulatory network governing TEF-4-mediated cellular processes. In summary, TEF-4 inhibitors offer a diverse toolkit for researchers to explore the specific functions of TEF-4 in various cellular processes. By selectively modulating key signaling pathways associated with TEF-4, these chemicals provide valuable insights into the regulatory mechanisms governing TEF-4-mediated transcriptional control, cell growth, and metabolism.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
AZD8055 | 1009298-09-2 | sc-364424 sc-364424A | 10 mg 50 mg | $160.00 $345.00 | 12 | |
AZD8055 is a selective inhibitor of the mTOR kinase, known for its impact on the mTOR signaling pathway. By targeting mTOR, this compound may indirectly influence TEF-4 by modulating downstream signaling cascades related to cellular growth, metabolism, and protein synthesis, potentially affecting TEF-4 expression or activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is an mTOR inhibitor with implications for TEF-4 regulation. Through its action on mTOR, Rapamycin can indirectly modulate TEF-4 by affecting signaling pathways involved in cell growth, proliferation, and metabolism. The compound provides a potential avenue for exploring TEF-4-related cellular processes and the intricate regulatory roles of mTOR in gene expression. | ||||||
PP242 | 1092351-67-1 | sc-301606A sc-301606 | 1 mg 5 mg | $56.00 $169.00 | 8 | |
PP242 is a dual mTORC1 and mTORC2 inhibitor, offering a means to influence TEF-4 through modulation of the mTOR signaling pathway. By targeting both mTOR complexes, PP242 may impact downstream signaling events associated with TEF-4, potentially affecting its expression or activity and providing insights into the regulatory mechanisms governing TEF-4-mediated cellular processes. | ||||||
Torin 1 | 1222998-36-8 | sc-396760 | 10 mg | $240.00 | 7 | |
Torin 1 is a potent mTOR inhibitor that can potentially influence TEF-4 regulation by targeting the mTOR signaling pathway. Its impact on mTOR may lead to downstream effects on TEF-4-related cellular processes, providing a tool for researchers to explore the specific functions of TEF-4 in various biological contexts. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor that may indirectly modulate TEF-4 through the PI3K/AKT signaling pathway. By inhibiting PI3K, this compound can affect downstream signaling events that intersect with TEF-4-related pathways, potentially influencing the expression or activity of TEF-4 and shedding light on the intricate regulatory network governing TEF-4-mediated cellular processes. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a PI3K inhibitor with potential implications for TEF-4 regulation. Through its action on PI3K, Wortmannin can indirectly influence TEF-4 by modulating downstream signaling cascades related to cell survival, growth, and proliferation. The compound provides a tool for researchers to explore the regulatory roles of PI3K in TEF-4-mediated cellular processes. | ||||||
BEZ235 | 915019-65-7 | sc-364429 | 50 mg | $207.00 | 8 | |
BEZ235 is a dual PI3K and mTOR inhibitor that may impact TEF-4 regulation through modulation of the PI3K/AKT/mTOR pathway. By targeting both PI3K and mTOR, BEZ235 can influence downstream signaling events associated with TEF-4, potentially affecting its expression or activity and offering insights into the interconnected signaling cascades governing TEF-4-mediated cellular processes. | ||||||
Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 | 612847-09-3 | sc-202048 sc-202048A | 1 mg 5 mg | $204.00 $265.00 | 29 | |
Akt Inhibitor VIII selectively targets the AKT signaling pathway, providing a potential avenue for indirect modulation of TEF-4. By inhibiting AKT, this compound may impact downstream events that intersect with TEF-4-related pathways, potentially influencing the expression or activity of TEF-4 and allowing researchers to probe the specific roles of TEF-4 in cellular processes. | ||||||
2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic Acid Ethyl Ester | 305834-79-1 | sc-479756 | 25 mg | $380.00 | ||
This compound, also called SC79, is an Akt activator that may indirectly influence TEF-4 through activation of the PI3K/AKT signaling pathway. By enhancing AKT activity, SC79 can potentially modulate downstream events associated with TEF-4, providing researchers with a unique tool to explore the regulatory roles of AKT in TEF-4-mediated cellular processes. | ||||||
MK-2206 dihydrochloride | 1032350-13-2 | sc-364537 sc-364537A | 5 mg 10 mg | $178.00 $325.00 | 67 | |
MK-2206 is a selective AKT inhibitor that can potentially modulate TEF-4 through inhibition of the PI3K/AKT signaling pathway. By targeting AKT, MK-2206 may affect downstream signaling events associated with TEF-4, potentially influencing its expression or activity and offering insights into the intricate regulatory network governing TEF-4-mediated cellular processes. | ||||||