TDAG51 activators belong to a specific category of chemical compounds that are known for their ability to modulate the TDAG51 protein, also referred to as T-cell death-associated gene 51. The TDAG51 protein, encoded by the T-cell death-associated gene, is a multifunctional protein primarily found in immune cells, such as T-cells and B-cells, but it is also expressed in various other tissues, including the brain, kidney, and heart. TDAG51 is recognized for its role in cellular stress responses, apoptosis (programmed cell death), and calcium signaling. Activators of TDAG51 are compounds that influence the function or activity of this protein in a specific manner.
The molecular mechanisms by which TDAG51 activators operate can vary, but they generally involve interactions with the TDAG51 protein, leading to alterations in its signaling pathways. These compounds can either enhance or inhibit TDAG51's functions, depending on their specific chemical properties and binding affinities. TDAG51 activators have drawn significant attention in basic research due to their potential implications in a range of cellular processes. Understanding the precise mechanisms by which these compounds modulate TDAG51 can shed light on fundamental biological processes and may have broader implications in fields such as immunology, cell biology, and neuroscience. Researchers are continually exploring the diverse roles and regulatory mechanisms of TDAG51 activators, contributing to our understanding of cellular biology and potential applications in various scientific contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Induces ER stress and activates the unfolded protein response (UPR) pathway, leading to TDAG51 expression. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Inhibits the sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA), causing calcium release and ER stress, leading to TDAG51 induction. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Disrupts protein transport between the Golgi apparatus and the endoplasmic reticulum, triggering ER stress and TDAG51 expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Activates glucocorticoid receptors, leading to the upregulation of TDAG51 gene transcription. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Acts as a histone deacetylase (HDAC) inhibitor, increasing histone acetylation and promoting TDAG51 expression. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
Disrupts glycolysis and induces ER stress, leading to TDAG51 expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylyl cyclase, increasing cAMP levels, which can upregulate TDAG51 gene expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Binds to retinoic acid receptors (RARs), influencing TDAG51 gene expression through RA signaling pathways. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
Inhibits thymidylate synthase and induces ER stress, leading to TDAG51 expression in certain cancer cells. | ||||||