Date published: 2026-2-14

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TCEA2 Inhibitors

The chemical class identified as TCEA2 Inhibitors encompasses a group of compounds meticulously designed to selectively target the molecular entity TCEA2. TCEA2, or Transcription Elongation Factor A2, is a protein involved in the regulation of transcription, specifically during the elongation phase of RNA synthesis. This transcription factor interacts with RNA polymerase II, facilitating the efficient elongation of nascent RNA chains. Despite the recognized importance of TCEA2 in cellular processes, the specific mechanisms and regulatory networks governing its functions are subjects of ongoing research within the fields of molecular biology and biochemistry. Inhibitors within the TCEA2 Inhibitors class are intricately engineered molecules with the primary objective of modulating the activity or function of TCEA2, thereby inducing an inhibitory effect. Researchers in this field adopt a multifaceted approach, integrating insights from structural biology, medicinal chemistry, and computational modeling to unravel the complex molecular interactions between the inhibitors and the target TCEA2.

Structurally, TCEA2 Inhibitors are characterized by specific molecular features designed to facilitate selective binding to TCEA2. This selectivity is crucial to minimize unintended effects on other cellular components, ensuring a focused impact on the intended molecular target. The development of inhibitors within this chemical class involves a comprehensive exploration of structure-activity relationships, optimization of pharmacokinetic properties, and a deep understanding of the molecular mechanisms associated with TCEA2. As researchers delve deeper into the functional aspects of TCEA2 Inhibitors, the knowledge generated contributes not only to deciphering the specific roles of TCEA2 but also to advancing our broader comprehension of the intricate processes governing transcriptional regulation and RNA synthesis within cells. The exploration of TCEA2 Inhibitors stands as a significant avenue for expanding fundamental knowledge in molecular pharmacology and cellular biology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Interacts with DNA and inhibits RNA polymerase, potentially leading to decreased transcription of many genes including TCEA2.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$269.00
$1050.00
26
(2)

A potent inhibitor of RNA polymerase II, which could lead to a general decrease in mRNA synthesis, potentially including TCEA2.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$43.00
$189.00
$316.00
$663.00
6
(1)

Inhibits RNA polymerase II transcriptional elongation, which could reduce the levels of transcripts including that of TCEA2.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$90.00
$204.00
13
(1)

Known to inhibit the activity of RNA polymerase I, II, and III, potentially reducing the transcription of TCEA2.

Flavopiridol

146426-40-6sc-202157
sc-202157A
5 mg
25 mg
$78.00
$259.00
41
(3)

Inhibits cyclin-dependent kinases (CDKs) which are necessary for transcription, potentially affecting TCEA2 expression.

Cordycepin

73-03-0sc-203902
10 mg
$101.00
5
(1)

Analog of adenosine that can terminate RNA transcription prematurely, which may include transcripts of genes like TCEA2.

(±)-JQ1

1268524-69-1sc-472932
sc-472932A
5 mg
25 mg
$231.00
$863.00
1
(0)

Inhibits BET bromodomain proteins, affecting chromatin structure and gene expression, potentially including TCEA2.

Rocaglamide

84573-16-0sc-203241
sc-203241A
sc-203241B
sc-203241C
sc-203241D
100 µg
1 mg
5 mg
10 mg
25 mg
$275.00
$474.00
$1639.00
$2497.00
$5344.00
4
(1)

A natural product that inhibits translation initiation and could indirectly affect the expression of TCEA2 at the translational level.

Sinefungin

58944-73-3sc-203263
sc-203263B
sc-203263C
sc-203263A
1 mg
100 mg
1 g
10 mg
$271.00
$5202.00
$40368.00
$704.00
4
(1)

A nucleoside analog that can inhibit methyltransferase enzymes, potentially affecting mRNA synthesis and gene expression.

RG 108

48208-26-0sc-204235
sc-204235A
10 mg
50 mg
$131.00
$515.00
2
(1)

A non-nucleoside DNA methyltransferase inhibitor, potentially leading to changes in DNA methylation status and gene expression including TCEA2.