Date published: 2025-10-25

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TC1 Inhibitors

TC1 inhibitors belong to a specific category of chemical compounds designed to target and inhibit the activity of the TC1 protein, also known as Tubulin cofactor C. TC1 plays a crucial role in cellular processes related to the formation and maintenance of the microtubule cytoskeleton. Microtubules are dynamic structural elements within cells that are essential for various cellular functions, including intracellular transport, cell division, and cell shape maintenance. TC1 functions as a cofactor that assists in the correct folding and assembly of α- and β-tubulin subunits into functional microtubules. Inhibitors of TC1 are primarily developed for research purposes, serving as valuable tools for scientists and researchers to investigate the molecular mechanisms and functions associated with this protein in the context of cytoskeletal dynamics and cellular processes.

TC1 inhibitors are typically composed of small molecules or chemical compounds specifically designed to interact with the TC1 protein, disrupting its normal function as a tubulin cofactor. By inhibiting TC1, these compounds can impact microtubule assembly and dynamics, leading to alterations in intracellular transport, cell division, and other microtubule-dependent processes. Researchers use TC1 inhibitors in laboratory settings to manipulate the activity of this protein and study its roles in cytoskeletal organization and cellular function. These inhibitors provide valuable insights into the molecular mechanisms by which TC1 influences microtubule dynamics and contribute to a deeper understanding of its significance in cellular biology. While TC1 inhibitors may have broader implications, their primary purpose is to assist scientists in deciphering the intricacies of TC1-mediated cytoskeletal processes.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Colchicine

64-86-8sc-203005
sc-203005A
sc-203005B
sc-203005C
sc-203005D
sc-203005E
1 g
5 g
50 g
100 g
500 g
1 kg
$98.00
$315.00
$2244.00
$4396.00
$17850.00
$34068.00
3
(2)

Colchicine binds to tubulin, inhibiting its polymerization and affecting microtubule formation, which may influence TBC expression.

Nocodazole

31430-18-9sc-3518B
sc-3518
sc-3518C
sc-3518A
5 mg
10 mg
25 mg
50 mg
$58.00
$83.00
$140.00
$242.00
38
(2)

Nocodazole disrupts microtubule polymerization and could impact the cellular need for TBC, potentially reducing its expression.

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
$40.00
$73.00
$217.00
$242.00
$724.00
$1196.00
39
(2)

Paclitaxel stabilizes microtubules and could alter the dynamics of tubulin, affecting the role and expression of TBC.

Podophyllotoxin

518-28-5sc-204853
100 mg
$82.00
1
(1)

Podophyllotoxin inhibits tubulin polymerization, potentially altering the cellular context for TBC expression.

Eribulin

253128-41-5sc-507547
5 mg
$865.00
(0)

Eribulin inhibits microtubule growth, potentially impacting the functional need for Tubulin cofactor C.

Griseofulvin

126-07-8sc-202171A
sc-202171
sc-202171B
5 mg
25 mg
100 mg
$83.00
$216.00
$586.00
4
(2)

Griseofulvin disrupts microtubule function by binding to tubulin, possibly influencing TBC expression indirectly.

Vinblastine

865-21-4sc-491749
sc-491749A
sc-491749B
sc-491749C
sc-491749D
10 mg
50 mg
100 mg
500 mg
1 g
$100.00
$230.00
$450.00
$1715.00
$2900.00
4
(0)

Vinblastine binds to tubulin and inhibits its assembly into microtubules, which could affect TBC expression levels.

Mebendazole

31431-39-7sc-204798
sc-204798A
5 g
25 g
$45.00
$87.00
2
(2)

Mebendazole disrupts microtubule synthesis, potentially altering the need and expression of tubulin cofactors.

Thiabendazole

148-79-8sc-204913
sc-204913A
sc-204913B
sc-204913C
sc-204913D
10 g
100 g
250 g
500 g
1 kg
$31.00
$82.00
$179.00
$306.00
$561.00
5
(1)

Thiabendazole inhibits microtubule polymerization, potentially affecting the cellular dynamics that regulate TBC expression.

Albendazole

54965-21-8sc-210771
100 mg
$209.00
1
(0)

Albendazole disrupts microtubule formation, which may indirectly lead to changes in TBC expression as the cell adjusts.