TC1 inhibitors belong to a specific category of chemical compounds designed to target and inhibit the activity of the TC1 protein, also known as Tubulin cofactor C. TC1 plays a crucial role in cellular processes related to the formation and maintenance of the microtubule cytoskeleton. Microtubules are dynamic structural elements within cells that are essential for various cellular functions, including intracellular transport, cell division, and cell shape maintenance. TC1 functions as a cofactor that assists in the correct folding and assembly of α- and β-tubulin subunits into functional microtubules. Inhibitors of TC1 are primarily developed for research purposes, serving as valuable tools for scientists and researchers to investigate the molecular mechanisms and functions associated with this protein in the context of cytoskeletal dynamics and cellular processes.
TC1 inhibitors are typically composed of small molecules or chemical compounds specifically designed to interact with the TC1 protein, disrupting its normal function as a tubulin cofactor. By inhibiting TC1, these compounds can impact microtubule assembly and dynamics, leading to alterations in intracellular transport, cell division, and other microtubule-dependent processes. Researchers use TC1 inhibitors in laboratory settings to manipulate the activity of this protein and study its roles in cytoskeletal organization and cellular function. These inhibitors provide valuable insights into the molecular mechanisms by which TC1 influences microtubule dynamics and contribute to a deeper understanding of its significance in cellular biology. While TC1 inhibitors may have broader implications, their primary purpose is to assist scientists in deciphering the intricacies of TC1-mediated cytoskeletal processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Colchicine binds to tubulin, inhibiting its polymerization and affecting microtubule formation, which may influence TBC expression. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole disrupts microtubule polymerization and could impact the cellular need for TBC, potentially reducing its expression. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Paclitaxel stabilizes microtubules and could alter the dynamics of tubulin, affecting the role and expression of TBC. | ||||||
Podophyllotoxin | 518-28-5 | sc-204853 | 100 mg | $82.00 | 1 | |
Podophyllotoxin inhibits tubulin polymerization, potentially altering the cellular context for TBC expression. | ||||||
Eribulin | 253128-41-5 | sc-507547 | 5 mg | $865.00 | ||
Eribulin inhibits microtubule growth, potentially impacting the functional need for Tubulin cofactor C. | ||||||
Griseofulvin | 126-07-8 | sc-202171A sc-202171 sc-202171B | 5 mg 25 mg 100 mg | $83.00 $216.00 $586.00 | 4 | |
Griseofulvin disrupts microtubule function by binding to tubulin, possibly influencing TBC expression indirectly. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $230.00 $450.00 $1715.00 $2900.00 | 4 | |
Vinblastine binds to tubulin and inhibits its assembly into microtubules, which could affect TBC expression levels. | ||||||
Mebendazole | 31431-39-7 | sc-204798 sc-204798A | 5 g 25 g | $45.00 $87.00 | 2 | |
Mebendazole disrupts microtubule synthesis, potentially altering the need and expression of tubulin cofactors. | ||||||
Thiabendazole | 148-79-8 | sc-204913 sc-204913A sc-204913B sc-204913C sc-204913D | 10 g 100 g 250 g 500 g 1 kg | $31.00 $82.00 $179.00 $306.00 $561.00 | 5 | |
Thiabendazole inhibits microtubule polymerization, potentially affecting the cellular dynamics that regulate TBC expression. | ||||||
Albendazole | 54965-21-8 | sc-210771 | 100 mg | $209.00 | 1 | |
Albendazole disrupts microtubule formation, which may indirectly lead to changes in TBC expression as the cell adjusts. | ||||||