TBRG1 Inhibitors
TBRG1 inhibitors encompass compounds that can indirectly suppress the functional activity of TBRG1 by interacting with various signaling pathways. TBRG1, also known as transforming growth factor beta regulator 1, does not have well-characterized direct chemical inhibitors, but there are several pathways through which its activity can be influenced. Inhibitors of the PI3K/AKT pathway, such as LY294002 and Wortmannin, can decrease the phosphorylation of downstream proteins, thereby potentially reducing the phosphorylation state of TBRG1 and its subsequent activity.
In addition,TBRG1 inhibitors encompass compounds that can indirectly suppress the functional activity of TBRG1 by interacting with various signaling pathways.
SEE ALSO...
Items 11 to 11 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
A multi-kinase inhibitor that targets RAF kinases, among others. Inhibition of RAF kinases leads to decreased signaling through the MAPK/ERK pathway, which could result in lower phosphorylation and activity of TBRG1. | ||||||