Date published: 2026-4-5

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T2R Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of T2R Antibodies for advanced research in the field of taste receptor biology. T2R Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). T2R proteins, or type 2 taste receptors, play a crucial role in the detection of bitter compounds, contributing to the sensory perception of taste and influencing dietary choices. The function of T2R proteins is essential for the identification of potentially harmful substances, thereby serving a protective role in human health. Understanding T2R signaling pathways can provide insights into various physiological processes and potential therapeutic targets. Research has shown that T2R proteins are expressed in multiple tissues beyond the tongue, suggesting broader physiological roles than initially understood. T2R signaling mechanisms have been linked to various cellular responses, including hormone secretion and smooth muscle relaxation. Ongoing studies continue to reveal new functions of T2R proteins in different biological systems. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of taste receptor biology and its impact on human health.

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T2R Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

T2R3 Antibody (E-12)

sc-398489mouse IgG1 λ72-89 (h)WB, IP, IF, ELISAm, r, h
1
(3)

T2R21 Antibody (D-8)

sc-514219mouse IgM κ148-167 (m)WB, IP, IF, ELISAm, r, h
1
(2)

T2R104 Antibody (H-5)

sc-515693mouse IgM κ73-89 (r)WB, IP, IF, ELISAm, r
1
(2)

T2R CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

T2R10 CRISPR/Cas9 KO Plasmid (h2)

sc-406031-KO-2hGene KnockoutGFP0
(0)

T2R10 HDR Plasmid (h2)

sc-406031-HDR-2hHomology Directed RepairPuromycin0
(0)

T2R14 Double Nickase Plasmid (h)

sc-410582-NIChGene KnockoutPuromycin0
(0)

T2R38 CRISPR/Cas9 KO Plasmid (h)

sc-402279hGene KnockoutGFP0
(0)

T2R38 Double Nickase Plasmid (h)

sc-402279-NIChGene KnockoutPuromycin0
(0)

T2R38 Double Nickase Plasmid (h2)

sc-402279-NIC-2hGene KnockoutPuromycin0
(0)

T2R38 Double Nickase Plasmid (m)

sc-436483-NICmGene KnockoutPuromycin0
(0)

T2R38 Double Nickase Plasmid (m2)

sc-436483-NIC-2mGene KnockoutPuromycin0
(0)

T2R CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

T2R38 CRISPR Activation Plasmid (h)

sc-402279-ACThGene ActivationPuro, Blast, Hygro0
(0)

T2R38 CRISPR Activation Plasmid (h2)

sc-402279-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

T2R siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

T2R1 siRNA (h)

sc-45338hGene SilencingN/A0
(0)

T2R1 shRNA Plasmid (h)

sc-45338-SHhGene SilencingPuromycin0
(0)

T2R1 shRNA (h) Lentiviral Particles

sc-45338-VhGene SilencingPuromycin0
(0)

T2R1 siRNA (m)

sc-154005mGene SilencingN/A0
(0)

T2R1 shRNA Plasmid (m)

sc-154005-SHmGene SilencingPuromycin0
(0)

T2R1 shRNA (m) Lentiviral Particles

sc-154005-VmGene SilencingPuromycin0
(0)

T2R3 siRNA (h)

sc-89478hGene SilencingN/A0
(0)

T2R3 shRNA Plasmid (h)

sc-89478-SHhGene SilencingPuromycin0
(0)

T2R3 shRNA (h) Lentiviral Particles

sc-89478-VhGene SilencingPuromycin0
(0)

T2R4 siRNA (h)

sc-89642hGene SilencingN/A0
(0)

T2R4 shRNA Plasmid (h)

sc-89642-SHhGene SilencingPuromycin0
(0)

T2R4 shRNA (h) Lentiviral Particles

sc-89642-VhGene SilencingPuromycin0
(0)

T2R4 siRNA (m)

sc-154023mGene SilencingN/A0
(0)

T2R4 shRNA Plasmid (m)

sc-154023-SHmGene SilencingPuromycin0
(0)

T2R4 shRNA (m) Lentiviral Particles

sc-154023-VmGene SilencingPuromycin0
(0)

T2R5 siRNA (h)

sc-89379hGene SilencingN/A0
(0)

T2R5 shRNA Plasmid (h)

sc-89379-SHhGene SilencingPuromycin0
(0)

T2R5 shRNA (h) Lentiviral Particles

sc-89379-VhGene SilencingPuromycin0
(0)

T2R6 siRNA (m)

sc-45337mGene SilencingN/A0
(0)

T2R6 shRNA Plasmid (m)

sc-45337-SHmGene SilencingPuromycin0
(0)

T2R6 shRNA (m) Lentiviral Particles

sc-45337-VmGene SilencingPuromycin0
(0)

T2R7 siRNA (h)

sc-45336hGene SilencingN/A0
(0)

T2R7 shRNA Plasmid (h)

sc-45336-SHhGene SilencingPuromycin0
(0)

T2R7 shRNA (h) Lentiviral Particles

sc-45336-VhGene SilencingPuromycin0
(0)

T2R8 siRNA (h)

sc-96156hGene SilencingN/A0
(0)

T2R8 shRNA Plasmid (h)

sc-96156-SHhGene SilencingPuromycin0
(0)

T2R8 shRNA (h) Lentiviral Particles

sc-96156-VhGene SilencingPuromycin0
(0)

T2R9 siRNA (h)

sc-95854hGene SilencingN/A0
(0)

T2R9 shRNA Plasmid (h)

sc-95854-SHhGene SilencingPuromycin0
(0)

T2R9 shRNA (h) Lentiviral Particles

sc-95854-VhGene SilencingPuromycin0
(0)

T2R05 siRNA (m)

sc-154001mGene SilencingN/A0
(0)

T2R05 shRNA Plasmid (m)

sc-154001-SHmGene SilencingPuromycin0
(0)

T2R05 shRNA (m) Lentiviral Particles

sc-154001-VmGene SilencingPuromycin0
(0)

T2R06 siRNA (m)

sc-154002mGene SilencingN/A0
(0)

T2R06 shRNA Plasmid (m)

sc-154002-SHmGene SilencingPuromycin0
(0)

T2R06 shRNA (m) Lentiviral Particles

sc-154002-VmGene SilencingPuromycin0
(0)

T2R07 siRNA (m)

sc-154003mGene SilencingN/A0
(0)

T2R07 shRNA Plasmid (m)

sc-154003-SHmGene SilencingPuromycin0
(0)

T2R07 shRNA (m) Lentiviral Particles

sc-154003-VmGene SilencingPuromycin0
(0)

T2R09 siRNA (m)

sc-154004mGene SilencingN/A0
(0)

T2R09 shRNA Plasmid (m)

sc-154004-SHmGene SilencingPuromycin0
(0)

T2R09 shRNA (m) Lentiviral Particles

sc-154004-VmGene SilencingPuromycin0
(0)

T2R10 siRNA (h)

sc-95848hGene SilencingN/A0
(0)

T2R10 shRNA Plasmid (h)

sc-95848-SHhGene SilencingPuromycin0
(0)

T2R10 shRNA (h) Lentiviral Particles

sc-95848-VhGene SilencingPuromycin0
(0)

T2R10 siRNA (m)

sc-154006mGene SilencingN/A0
(0)

T2R10 shRNA Plasmid (m)

sc-154006-SHmGene SilencingPuromycin0
(0)

T2R10 shRNA (m) Lentiviral Particles

sc-154006-VmGene SilencingPuromycin0
(0)

T2R13 siRNA (h)

sc-96215hGene SilencingN/A0
(0)

T2R13 shRNA Plasmid (h)

sc-96215-SHhGene SilencingPuromycin0
(0)

T2R13 shRNA (h) Lentiviral Particles

sc-96215-VhGene SilencingPuromycin0
(0)

T2R14 siRNA (h)

sc-95889hGene SilencingN/A0
(0)

T2R14 shRNA Plasmid (h)

sc-95889-SHhGene SilencingPuromycin0
(0)

T2R14 shRNA (h) Lentiviral Particles

sc-95889-VhGene SilencingPuromycin0
(0)

T2R15 siRNA (m)

sc-154009mGene SilencingN/A0
(0)

T2R15 shRNA Plasmid (m)

sc-154009-SHmGene SilencingPuromycin0
(0)

T2R15 shRNA (m) Lentiviral Particles

sc-154009-VmGene SilencingPuromycin0
(0)

T2R16 siRNA (h)

sc-89454hGene SilencingN/A0
(0)

T2R16 shRNA Plasmid (h)

sc-89454-SHhGene SilencingPuromycin0
(0)

T2R16 shRNA (h) Lentiviral Particles

sc-89454-VhGene SilencingPuromycin0
(0)

T2R16 siRNA (m)

sc-154010mGene SilencingN/A0
(0)

T2R16 shRNA Plasmid (m)

sc-154010-SHmGene SilencingPuromycin0
(0)

T2R16 shRNA (m) Lentiviral Particles

sc-154010-VmGene SilencingPuromycin0
(0)

T2R17 siRNA (m)

sc-154011mGene SilencingN/A0
(0)

T2R17 shRNA Plasmid (m)

sc-154011-SHmGene SilencingPuromycin0
(0)

T2R17 shRNA (m) Lentiviral Particles

sc-154011-VmGene SilencingPuromycin0
(0)

T2R18 siRNA (m)

sc-154012mGene SilencingN/A0
(0)

T2R18 shRNA Plasmid (m)

sc-154012-SHmGene SilencingPuromycin0
(0)

T2R18 shRNA (m) Lentiviral Particles

sc-154012-VmGene SilencingPuromycin0
(0)

T2R20 siRNA (m)

sc-154013mGene SilencingN/A0
(0)

T2R20 shRNA Plasmid (m)

sc-154013-SHmGene SilencingPuromycin0
(0)

T2R20 shRNA (m) Lentiviral Particles

sc-154013-VmGene SilencingPuromycin0
(0)

T2R21 siRNA (m)

sc-154014mGene SilencingN/A0
(0)

T2R21 shRNA Plasmid (m)

sc-154014-SHmGene SilencingPuromycin0
(0)

T2R21 shRNA (m) Lentiviral Particles

sc-154014-VmGene SilencingPuromycin0
(0)

T2R22 siRNA (m)

sc-154015mGene SilencingN/A0
(0)

T2R22 shRNA Plasmid (m)

sc-154015-SHmGene SilencingPuromycin0
(0)

T2R22 shRNA (m) Lentiviral Particles

sc-154015-VmGene SilencingPuromycin0
(0)

T2R23 siRNA (m)

sc-154016mGene SilencingN/A0
(0)

T2R23 shRNA Plasmid (m)

sc-154016-SHmGene SilencingPuromycin0
(0)

T2R23 shRNA (m) Lentiviral Particles

sc-154016-VmGene SilencingPuromycin0
(0)

T2R24 siRNA (m)

sc-154017mGene SilencingN/A0
(0)

T2R24 shRNA Plasmid (m)

sc-154017-SHmGene SilencingPuromycin0
(0)

T2R24 shRNA (m) Lentiviral Particles

sc-154017-VmGene SilencingPuromycin0
(0)

T2R26 siRNA (m)

sc-154018mGene SilencingN/A0
(0)

T2R26 shRNA Plasmid (m)

sc-154018-SHmGene SilencingPuromycin0
(0)

T2R26 shRNA (m) Lentiviral Particles

sc-154018-VmGene SilencingPuromycin0
(0)

T2R29 siRNA (m)

sc-154019mGene SilencingN/A0
(0)

T2R29 shRNA Plasmid (m)

sc-154019-SHmGene SilencingPuromycin0
(0)

T2R29 shRNA (m) Lentiviral Particles

sc-154019-VmGene SilencingPuromycin0
(0)

T2R31 siRNA (m)

sc-154020mGene SilencingN/A0
(0)

T2R31 shRNA Plasmid (m)

sc-154020-SHmGene SilencingPuromycin0
(0)

T2R31 shRNA (m) Lentiviral Particles

sc-154020-VmGene SilencingPuromycin0
(0)

T2R37 siRNA (m)

sc-154021mGene SilencingN/A0
(0)

T2R37 shRNA Plasmid (m)

sc-154021-SHmGene SilencingPuromycin0
(0)

T2R37 shRNA (m) Lentiviral Particles

sc-154021-VmGene SilencingPuromycin0
(0)

T2R38 siRNA (h)

sc-45339hGene SilencingN/A0
(0)

T2R38 shRNA Plasmid (h)

sc-45339-SHhGene SilencingPuromycin0
(0)

T2R38 shRNA (h) Lentiviral Particles

sc-45339-VhGene SilencingPuromycin0
(0)

T2R38 siRNA (m)

sc-45340mGene SilencingN/A0
(0)

T2R38 shRNA Plasmid (m)

sc-45340-SHmGene SilencingPuromycin0
(0)

T2R38 shRNA (m) Lentiviral Particles

sc-45340-VmGene SilencingPuromycin0
(0)

T2R39 siRNA (h)

sc-89846hGene SilencingN/A0
(0)

T2R39 shRNA Plasmid (h)

sc-89846-SHhGene SilencingPuromycin0
(0)

T2R39 shRNA (h) Lentiviral Particles

sc-89846-VhGene SilencingPuromycin0
(0)

T2R39 siRNA (m)

sc-154022mGene SilencingN/A0
(0)

T2R39 shRNA Plasmid (m)

sc-154022-SHmGene SilencingPuromycin0
(0)

T2R39 shRNA (m) Lentiviral Particles

sc-154022-VmGene SilencingPuromycin0
(0)

T2R40 siRNA (h)

sc-89669hGene SilencingN/A0
(0)

T2R40 shRNA Plasmid (h)

sc-89669-SHhGene SilencingPuromycin0
(0)

T2R40 shRNA (h) Lentiviral Particles

sc-89669-VhGene SilencingPuromycin0
(0)

T2R41 siRNA (h)

sc-89717hGene SilencingN/A0
(0)

T2R41 shRNA Plasmid (h)

sc-89717-SHhGene SilencingPuromycin0
(0)

T2R41 shRNA (h) Lentiviral Particles

sc-89717-VhGene SilencingPuromycin0
(0)

T2R41 siRNA (m)

sc-154025mGene SilencingN/A0
(0)

T2R41 shRNA Plasmid (m)

sc-154025-SHmGene SilencingPuromycin0
(0)

T2R41 shRNA (m) Lentiviral Particles

sc-154025-VmGene SilencingPuromycin0
(0)

T2R42 siRNA (h)

sc-96186hGene SilencingN/A0
(0)

T2R42 shRNA Plasmid (h)

sc-96186-SHhGene SilencingPuromycin0
(0)

T2R42 shRNA (h) Lentiviral Particles

sc-96186-VhGene SilencingPuromycin0
(0)

T2R43 siRNA (h)

sc-106590hGene SilencingN/A0
(0)

T2R43 shRNA Plasmid (h)

sc-106590-SHhGene SilencingPuromycin0
(0)

T2R43 shRNA (h) Lentiviral Particles

sc-106590-VhGene SilencingPuromycin0
(0)

T2R44 siRNA (h)

sc-106591hGene SilencingN/A0
(0)

T2R44 shRNA Plasmid (h)

sc-106591-SHhGene SilencingPuromycin0
(0)

T2R44 shRNA (h) Lentiviral Particles

sc-106591-VhGene SilencingPuromycin0
(0)

T2R44 siRNA (m)

sc-154026mGene SilencingN/A0
(0)

T2R44 shRNA Plasmid (m)

sc-154026-SHmGene SilencingPuromycin0
(0)

T2R44 shRNA (m) Lentiviral Particles

sc-154026-VmGene SilencingPuromycin0
(0)

T2R46 siRNA (h)

sc-106592hGene SilencingN/A0
(0)

T2R46 shRNA Plasmid (h)

sc-106592-SHhGene SilencingPuromycin0
(0)

T2R46 shRNA (h) Lentiviral Particles

sc-106592-VhGene SilencingPuromycin0
(0)

T2R47 siRNA (h)

sc-45577hGene SilencingN/A0
(0)

T2R47 shRNA Plasmid (h)

sc-45577-SHhGene SilencingPuromycin0
(0)

T2R47 shRNA (h) Lentiviral Particles

sc-45577-VhGene SilencingPuromycin0
(0)

T2R48 siRNA (h)

sc-96006hGene SilencingN/A0
(0)

T2R48 shRNA Plasmid (h)

sc-96006-SHhGene SilencingPuromycin0
(0)

T2R48 shRNA (h) Lentiviral Particles

sc-96006-VhGene SilencingPuromycin0
(0)

T2R49 siRNA (h)

sc-45449hGene SilencingN/A0
(0)

T2R49 shRNA Plasmid (h)

sc-45449-SHhGene SilencingPuromycin0
(0)

T2R49 shRNA (h) Lentiviral Particles

sc-45449-VhGene SilencingPuromycin0
(0)

T2R50 siRNA (h)

sc-45452hGene SilencingN/A0
(0)

T2R50 shRNA Plasmid (h)

sc-45452-SHhGene SilencingPuromycin0
(0)

T2R50 shRNA (h) Lentiviral Particles

sc-45452-VhGene SilencingPuromycin0
(0)

T2R60 siRNA (h)

sc-89617hGene SilencingN/A0
(0)

T2R60 shRNA Plasmid (h)

sc-89617-SHhGene SilencingPuromycin0
(0)

T2R60 shRNA (h) Lentiviral Particles

sc-89617-VhGene SilencingPuromycin0
(0)

T2R60 siRNA (m)

sc-154027mGene SilencingN/A0
(0)

T2R60 shRNA Plasmid (m)

sc-154027-SHmGene SilencingPuromycin0
(0)

T2R60 shRNA (m) Lentiviral Particles

sc-154027-VmGene SilencingPuromycin0
(0)

T2R104 siRNA (m)

sc-154000mGene SilencingN/A0
(0)

T2R104 shRNA Plasmid (m)

sc-154000-SHmGene SilencingPuromycin0
(0)

T2R104 shRNA (m) Lentiviral Particles

sc-154000-VmGene SilencingPuromycin0
(0)

T2R134 siRNA (m)

sc-154008mGene SilencingN/A0
(0)

T2R134 shRNA Plasmid (m)

sc-154008-SHmGene SilencingPuromycin0
(0)

T2R134 shRNA (m) Lentiviral Particles

sc-154008-VmGene SilencingPuromycin0
(0)