T2R104 Antibody (H-5): sc-515693

T2R104 Antibody (H-5) is a mouse monoclonal IgM antibody that detects T2R104 of mouse and rat origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-T2R104 antibody (H-5) is available as the non-conjugated form. T2R104, also known as taste receptor, type 2, member 104, is a 302 amino acid protein that belongs to the G-protein coupled receptor T2R family, which plays a crucial role in the perception of bitter compounds. T2R104 is primarily localized to the cell membrane, where T2R104 is strategically positioned to detect bitter tastants in the oral cavity and gastrointestinal tract, thereby contributing to the organism′s ability to identify potentially harmful substances in food. The gene encoding T2R104 is located on mouse chromosome 6 F3, and T2R104 expression in single taste receptor cells allows for the recognition of multiple tastants, enhancing the sensory capabilities of the organism. Anti-T2R104 antibody (H-5) enables researchers to explore the intricate mechanisms of taste perception and the physiological implications of bitter taste recognition in different species.

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T2R104 Antibody (H-5) References:

1. T2Rs function as bitter taste receptors.  |  Chandrashekar, J., et al. 2000. Cell. 100: 703-11. PMID: 10761935
2. A family of candidate taste receptors in human and mouse.  |  Matsunami, H., et al. 2000. Nature. 404: 601-4. PMID: 10766242
3. A plethora of taste receptors.  |  Kinnamon, SC. 2000. Neuron. 25: 507-10. PMID: 10774719
4. Identification of coding single-nucleotide polymorphisms in human taste receptor genes involving bitter tasting.  |  Ueda, T., et al. 2001. Biochem Biophys Res Commun. 285: 147-51. PMID: 11437385
5. Molecular mechanisms of bitter and sweet taste transduction.  |  Margolskee, RF. 2002. J Biol Chem. 277: 1-4. PMID: 11696554
6. Receptors for bitter and sweet taste.  |  Montmayeur, JP. and Matsunami, H. 2002. Curr Opin Neurobiol. 12: 366-71. PMID: 12139982
7. Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.  |  Zhang, Y., et al. 2003. Cell. 112: 293-301. PMID: 12581520
8. Evolution of bitter taste receptors in humans and apes.  |  Fischer, A., et al. 2005. Mol Biol Evol. 22: 432-6. PMID: 15496549
9. Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.  |  Go, Y., et al. 2005. Genetics. 170: 313-26. PMID: 15744053

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-T2R104 Antibody (H-5) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-T2R104 Antibody (H-5) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

T2R104 Antibody (H-5) Specifications

Alternate Product Name: T2R104

Product Clone Name: H-5

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 73-89

Epitope Target: T2R104

Epitope Species: rat

Product Reactivity/Detection: T2R104

Species Reactivity/Detection: mouse, rat

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for T2R104 Antibody (H-5): N/A