Stem Cell Reagents
Items 51 to 60 of 202 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Kenpaullone | 142273-20-9 | sc-200643 sc-200643A sc-200643B sc-200643C | 1 mg 5 mg 10 mg 25 mg | $60.00 $150.00 $226.00 $495.00 | 1 | |
Kenpaullone is a selective inhibitor of cyclin-dependent kinases, influencing cell cycle regulation and differentiation in stem cells. Its unique ability to modulate signaling pathways, particularly those involving Wnt and Notch, enhances stem cell maintenance and proliferation. By altering gene expression profiles, Kenpaullone promotes specific lineage commitment, making it a valuable reagent for investigating stem cell dynamics and fate decisions in developmental biology. | ||||||
PD173074 | 219580-11-7 | sc-202610 sc-202610A sc-202610B | 1 mg 5 mg 50 mg | $46.00 $140.00 $680.00 | 16 | |
PD173074 is a potent small molecule that selectively inhibits fibroblast growth factor receptor (FGFR) signaling, crucial for stem cell self-renewal and differentiation. Its unique interaction with the ATP-binding site of FGFR leads to altered downstream signaling cascades, impacting cellular proliferation and fate. By modulating key pathways, PD173074 serves as an essential tool for dissecting the molecular mechanisms underlying stem cell behavior and lineage specification. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Y-27632, free base, is a selective Rho-associated protein kinase (ROCK) inhibitor that plays a pivotal role in regulating cytoskeletal dynamics and cell adhesion. By disrupting RhoA signaling, it enhances cell survival and promotes the maintenance of pluripotency in stem cells. Its ability to modulate actin filament organization and focal adhesion dynamics allows for improved cell culture conditions, facilitating the study of stem cell behavior and differentiation pathways. | ||||||
16,16-Dimethyl-prostaglandin E2 | 39746-25-3 | sc-201240 sc-201240B sc-201240A | 1 mg 5 mg 10 mg | $145.00 $502.00 $949.00 | 2 | |
16,16-Dimethyl-prostaglandin E2 is a potent modulator of cellular signaling pathways, particularly influencing the balance between proliferation and differentiation in stem cells. It interacts with specific G-protein coupled receptors, triggering cascades that enhance cell migration and survival. This compound also plays a role in regulating gene expression through epigenetic modifications, thereby impacting stem cell fate decisions and enhancing the efficiency of reprogramming processes. | ||||||
Purvalanol A | 212844-53-6 | sc-224244 sc-224244A | 1 mg 5 mg | $71.00 $291.00 | 4 | |
Purvalanol A is a selective inhibitor of cyclin-dependent kinases, crucial for regulating the cell cycle in stem cells. By disrupting kinase activity, it alters phosphorylation patterns, leading to changes in cell cycle progression and differentiation. This compound also influences signaling pathways associated with cellular growth and survival, enhancing the maintenance of stemness. Its unique ability to modulate kinase interactions makes it a valuable tool in stem cell research. | ||||||
Tubacin | 537049-40-4 | sc-362815 sc-362815A sc-362815B sc-362815C sc-362815D | 1 mg 5 mg 50 mg 500 mg 1 g | $197.00 $429.00 $4249.00 $10543.00 $13674.00 | 8 | |
Tubacin is a potent inhibitor of histone deacetylases, specifically targeting HDAC6, which plays a pivotal role in regulating protein acetylation. By disrupting the deacetylation process, Tubacin enhances the acetylation of tubulin and other substrates, influencing cytoskeletal dynamics and cellular signaling pathways. This modulation promotes the maintenance of stem cell pluripotency and self-renewal, making Tubacin a significant reagent in stem cell studies. Its selective action on HDAC6 underscores its unique role in cellular regulation. | ||||||
7-Deacetyl-7-O-hemisuccinyl-Forskolin | 83797-56-2 | sc-203959 sc-203959A | 1 mg 5 mg | $204.00 $979.00 | ||
7-Deacetyl-7-O-hemisuccinyl-Forskolin is a specialized reagent that modulates intracellular signaling pathways by influencing cyclic AMP levels. Its unique structure allows for enhanced interaction with adenylate cyclase, promoting the activation of protein kinase A. This activation leads to downstream effects on gene expression and cellular differentiation, making it a valuable tool in stem cell research. Its distinct mechanism of action highlights its potential in studying stem cell behavior and fate determination. | ||||||
Apicidin | 183506-66-3 | sc-202061 sc-202061A | 1 mg 5 mg | $108.00 $336.00 | 9 | |
Apicidin is a potent stem cell reagent known for its ability to inhibit histone deacetylases, thereby altering chromatin structure and enhancing gene expression. This modulation of epigenetic regulation facilitates the maintenance of pluripotency in stem cells. By influencing specific signaling pathways, Apicidin promotes cellular reprogramming and differentiation, making it a critical component in the study of stem cell dynamics and developmental biology. Its unique interaction with histones underscores its role in epigenetic research. | ||||||
Scriptaid | 287383-59-9 | sc-202807 sc-202807A | 1 mg 5 mg | $63.00 $179.00 | 11 | |
Scriptaid is a selective inhibitor of histone deacetylases that plays a crucial role in modulating epigenetic landscapes within stem cells. By disrupting the deacetylation process, it enhances histone acetylation, leading to a more open chromatin configuration. This alteration promotes the activation of pluripotency-associated genes and influences key signaling pathways, thereby supporting cellular reprogramming and differentiation. Its distinct mechanism of action makes it a valuable tool in epigenetic studies. | ||||||
Quercetin Dihydrate | 6151-25-3 | sc-203225 sc-203225A | 5 g 25 g | $35.00 $60.00 | 1 | |
Quercetin Dihydrate is a flavonoid that exhibits unique interactions with cellular signaling pathways, particularly those involved in stem cell maintenance and differentiation. It modulates oxidative stress responses and influences the expression of key transcription factors. By enhancing the activity of certain kinases, it can promote cellular resilience and adaptability. Its ability to interact with various cellular receptors further underscores its role in regulating stem cell behavior and fate decisions. | ||||||