STEAP2 Activators
STEAP2 Activators, through their influence on metal ion concentrations and redox state within cells, play a pivotal role in modulating the activity of STEAP2. Compounds such as Ammonium iron(III) citrate, Copper(II) Sulfate, Zinc sulfate solution, and Manganese(II) Sulfate contribute to increasing the respective metal ion levels within cells. This elevation in metal ion concentration, particularly iron, copper, zinc, and manganese, potentially stimulates the metalloreductase activity of STEAP2. As a protein involved in the reduction of metal ions, STEAP2's activity is likely to be enhanced in response to increased availability of these ions, thereby facilitating their uptake and utilization in cellular processes. Additionally, Ferrous Sulfate and Iron(III) citrate tribasic monohydrate, by raising iron levels, indirectly influence STEAP2 activity, underscoring its role in iron homeostasis and reduction.
Furthermore, antioxidants and reducing agents like L-Ascorbic acid, free acid, NAD+, Free Acid, (-)-Epigallocatechin Gallate, Quercetin, Resveratrol, and α-Lipoic Acid play a significant role in affecting the cellular redox state. These compounds, through their redox-modulating properties, may indirectly enhance the reductive function of STEAP2. The altered redox environment could potentially stimulate STEAP2's activity in reducing metal ions, a critical aspect of its function in metal ion homeostasis. This indicates a complex interplay between STEAP2 activity and the cellular redox balance, highlighting the protein's sensitivity to changes in the redox state and metal ion concentrations. The combined effect of these activators, with their varied mechanisms of action, illustrates the multifaceted regulation of STEAP2, emphasizing its critical role in metal ion reduction and the maintenance of cellular metal homeostasis.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $46.00 $122.00 $189.00 | 3 | |
Copper(II) Sulfate, by elevating intracellular copper levels, may indirectly stimulate STEAP2 activity. STEAP2 has a role in copper reduction, and enhanced copper levels could trigger its reductive function. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc sulfate solution increases zinc levels in cells, potentially enhancing STEAP2 activity. STEAP2 is involved in metal ion reduction, and elevated zinc levels might stimulate its metalloreductase activity. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $46.00 | 5 | |
Ascorbic Acid, known for its reducing properties, may indirectly enhance the reductive function of STEAP2. By altering the redox state, it could stimulate STEAP2's metal ion reduction activity. | ||||||
Iron(II) sulfate solution | 10028-21-4 | sc-224024 | 1 each | $46.00 | ||
Ferrous Sulfate increases iron availability, potentially enhancing STEAP2 activity. STEAP2, involved in iron reduction, might respond to elevated iron levels by increasing its reductive activity. | ||||||
Ammonium iron(III) citrate | 1185-57-5 | sc-227256 sc-227256A sc-227256B sc-227256C | 100 g 1 kg 5 kg 10 kg | $50.00 $84.00 $374.00 $697.00 | 2 | |
Ammonium iron(III) citrate increases intracellular iron, which can indirectly enhance STEAP2 activity. STEAP2 functions in iron reduction, and increased iron levels could stimulate its iron-reducing activity to maintain iron homeostasis. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $57.00 $191.00 $302.00 $450.00 $1800.00 $3570.00 $10710.00 | 4 | |
NAD+, Free Acid, as a reducing agent, may indirectly influence STEAP2 activity. STEAP2's role in metal ion reduction could be enhanced in the presence of reducing agents like NADH. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
(-)-Epigallocatechin Gallate, with antioxidant properties, may indirectly enhance STEAP2 activity by affecting the cellular redox state, potentially stimulating its metalloreductase function. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, an antioxidant, may indirectly stimulate STEAP2 activity. Its impact on cellular redox balance could enhance STEAP2's function in metal ion reduction. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, known for its antioxidant effects, could indirectly enhance STEAP2 activity by influencing the redox state, potentially stimulating its metal ion reduction capacity. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
α-Lipoic Acid, as an antioxidant, may indirectly stimulate STEAP2's reductive function. Its role in altering the redox balance could enhance STEAP2's activity in reducing metal ions. | ||||||