Stat2 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Fludarabine | 21679-14-1 | sc-204755 sc-204755A | 5 mg 25 mg | $58.00 $204.00 | 15 | |
Fludarabine is a nucleoside analog used as an anti-cancer drug. It inhibits Stat2 activation by affecting DNA synthesis and repair, leading to reduced JAK-STAT signaling and impaired transcriptional activity of Stat2. | ||||||
Nifuroxazide | 965-52-6 | sc-204128 sc-204128A | 500 mg 5 g | $203.00 $520.00 | 5 | |
Nifuroxazide is an antibiotic that inhibits Stat2 signaling by interfering with the JAK-STAT pathway. It suppresses Stat2 phosphorylation, resulting in reduced transcriptional activation and modulation of interferon signaling. | ||||||
Stat3 inhibitor V, stattic | 19983-44-9 | sc-202818 sc-202818A sc-202818B sc-202818C sc-202818D sc-202818E sc-202818F | 25 mg 100 mg 250 mg 500 mg 1 g 2.5 g 5 g | $130.00 $196.00 $274.00 $512.00 $731.00 $1408.00 $2091.00 | 114 | |
Stattic is a small molecule inhibitor of Stat3 that also exhibits inhibitory effects on Stat2. It blocks Stat2 phosphorylation, leading to the inhibition of Stat2-mediated gene transcription and signaling in response to cytokines. | ||||||
Stat3 Inhibitor VI, S3I-201 | 501919-59-1 | sc-204304 | 10 mg | $151.00 | 104 | |
S3I-201 is a selective inhibitor of Stat3 and Stat2 dimerization, blocking their transcriptional activity. It disrupts the interaction between Stat3 and Stat2, inhibiting gene expression mediated by both proteins in the JAK-STAT signaling pathway. | ||||||
Emodin | 518-82-1 | sc-202601 sc-202601A sc-202601B | 50 mg 250 mg 15 g | $105.00 $214.00 $6255.00 | 2 | |
Emodin is a natural compound with inhibitory effects on Stat2 phosphorylation. It reduces the activation of Stat2 by interfering with JAK-STAT signaling, leading to the modulation of interferon-stimulated gene expression. | ||||||
Cucurbitacin I | 2222-07-3 | sc-203010 | 1 mg | $250.00 | 9 | |
Cucurbitacin I is a natural product that inhibits Stat2 activation by blocking JAK-STAT signaling. It downregulates Stat2 phosphorylation, leading to impaired interferon signaling and transcriptional activity of Stat2. | ||||||
AG-490 | 133550-30-8 | sc-202046C sc-202046A sc-202046B sc-202046 | 5 mg 50 mg 25 mg 10 mg | $84.00 $329.00 $223.00 $87.00 | 35 | |
AG-490 is a JAK-STAT signaling inhibitor that indirectly affects Stat2. By inhibiting JAK kinases, it suppresses Stat2 phosphorylation, leading to the downregulation of Stat2-mediated gene transcription and interferon signaling. | ||||||
Naringenin | 480-41-1 | sc-219338 | 25 g | $245.00 | 11 | |
Naringenin is a flavonoid compound that exhibits inhibitory effects on Stat2 phosphorylation. It modulates JAK-STAT signaling and reduces the transcriptional activation of Stat2, leading to the downregulation of interferon-stimulated genes. | ||||||
SIRT2 Inhibitor, AGK2 | 304896-28-4 | sc-202813A sc-202813 sc-202813B sc-202813C | 1 mg 5 mg 10 mg 25 mg | $46.00 $148.00 $316.00 $490.00 | 5 | |
AGK2 is an inhibitor of SIRT2, which indirectly affects Stat2 signaling. It modulates the acetylation status of Stat2, impacting its transcriptional activity and gene expression in the JAK-STAT pathway. | ||||||
Pyrimethamine | 58-14-0 | sc-208190 sc-208190A sc-208190B | 1 g 5 g 25 g | $80.00 $238.00 $825.00 | 5 | |
Pyrimethamine is an antimalarial drug that has been suggested to inhibit Stat2 phosphorylation. It impacts JAK-STAT signaling, leading to reduced Stat2 activation and altered transcription of interferon-stimulated genes. | ||||||