ST8Sia V Activators
ST8Sia V activators encompass a range of chemical compounds that enhance the enzyme's functionality, particularly in the biosynthesis of polysialic acid, a process crucial for neural development. Central to the activity of ST8Sia V is the availability of specific substrates and cofactors. CMP-Neu5Ac stands out as a direct substrate, essential for the sialylation process mediated by ST8Sia V. The presence of essential ions, such as calcium from Calcium Chloride, manganese from Manganese(II) Chloride, and magnesium from Magnesium Chloride, is crucial as they serve as cofactors, enhancing the catalytic efficiency of ST8Sia V. These ions ensure the enzyme operates at its optimal functional capacity.
Additionally, compounds like Sodium Cacodylate and Uridine Diphosphate (UDP) play supportive roles in maintaining an optimal enzymatic environment and balancing the glycosylation reaction components, indirectly facilitating ST8Sia V activity. The role of osmolytes and metabolic intermediates such as Betaine and Phosphoenolpyruvate is also significant. They contribute to cellular homeostasis and energy supply, respectively, essential for the efficient functioning of ST8Sia V. Furthermore, the availability of monosaccharides and precursors like Glucosamine, Galactose, N-Acetylmannosamine, and Fucose indirectly influences ST8Sia V activity. These compounds contribute to the synthesis of glycoproteins and complex sugars, providing a diverse range of substrates for ST8Sia V-mediated sialylation. Collectively, these activators play a pivotal role in enhancing the functional activity of ST8Sia V, thereby supporting its crucial role in neural development and cellular communication.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Calcium chloride anhydrous | 10043-52-4 | sc-207392 sc-207392A | 100 g 500 g | $65.00 $262.00 | 1 | |
Provides essential calcium ions as cofactors for ST8Sia V, enhancing its enzymatic activity. | ||||||
Manganese(II) chloride beads | 7773-01-5 | sc-252989 sc-252989A | 100 g 500 g | $19.00 $30.00 | ||
Acts as a cofactor for ST8Sia V, facilitating its catalytic process in sialic acid transfer. | ||||||
Magnesium chloride | 7786-30-3 | sc-255260C sc-255260B sc-255260 sc-255260A | 10 g 25 g 100 g 500 g | $27.00 $34.00 $47.00 $123.00 | 2 | |
Provides magnesium ions necessary for the stability and function of ST8Sia V. | ||||||
Uridine 5′-diphosphate sodium salt | 21931-53-3 | sc-222401 sc-222401A | 25 mg 100 mg | $37.00 $77.00 | ||
Involved in glycosylation reactions, its balance ensures enhanced ST8Sia V activity. | ||||||
Betaine | 107-43-7 | sc-214595 sc-214595A sc-214595B sc-214595C sc-214595D sc-214595E | 50 g 100 g 250 g 1 kg 2.5 kg 5 kg | $30.00 $40.00 $55.00 $160.00 $330.00 $580.00 | 2 | |
Acts as an osmolyte and methyl donor, maintaining cellular homeostasis essential for ST8Sia V function. | ||||||
D-Glucosamine | 3416-24-8 | sc-278917A sc-278917 | 1 g 10 g | $197.00 $764.00 | ||
A substrate for glycosaminoglycan synthesis, contributing to the overall glycosylation substrate pool, indirectly enhancing ST8Sia V activity. | ||||||
D-Galactose | 59-23-4 | sc-202564 | 100 g | $224.00 | 4 | |
A monosaccharide involved in glycosylation, influencing ST8Sia V activity by contributing to glycoprotein and complex sugar synthesis. | ||||||
N-Acetylneuraminic acid | 131-48-6 | sc-281055A sc-281055 sc-281055D sc-281055B sc-281055C | 1 g 5 g 25 g 100 g 250 g | $82.00 $153.00 $320.00 $572.00 $1336.00 | ||
A precursor in sialic acid biosynthesis, its availability enhances ST8Sia V activity by ensuring sufficient sialic acid supply for polysialylation. | ||||||
L-(−)-Fucose | 2438-80-4 | sc-221792 sc-221792A sc-221792B sc-221792C | 10 mg 5 g 50 g 100 g | $30.00 $150.00 $445.00 $824.00 | ||
Plays a role in glycosylation, supporting ST8Sia V activity by contributing to the diversity and complexity of glycan structures, which are substrates for sialylation. | ||||||