Date published: 2025-11-21

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D-Galactose (CAS 59-23-4)

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Application:
D-Galactose is the C-4 epimer of glucose
CAS Number:
59-23-4
Purity:
≥98%
Molecular Weight:
180.2
Molecular Formula:
C6H12O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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D-Galactose is a monosaccharide sugar used in research applications to study cellular metabolism and energy production processes. In biochemical assays, D-Galactose is often utilized to investigate the activity of the enzyme galactose-1-phosphate uridylyltransferase, which plays a key role in the Leloir pathway of galactose metabolism. This sugar is also used in studies of yeast and bacterial fermentation, as it serves as an alternative carbon source for organisms that possess the necessary enzymes for its utilization. Additionally, D-Galactose is employed in the synthesis of glycoproteins and glycolipids in various cell culture systems, aiding in the exploration of cell surface phenomena and molecular recognition. Its role in the formation of the extracellular matrix is another area of research interest, as D-Galactose-containing polysaccharides are integral to the structure and function of connective tissues.


D-Galactose (CAS 59-23-4) References

  1. D-galactose as a vector for prodrug design.  |  Melisi, D., et al. 2011. Curr Top Med Chem. 11: 2288-98. PMID: 21671867
  2. D-galactose-induced brain ageing model: A systematic review and meta-analysis on cognitive outcomes and oxidative stress indices.  |  Sadigh-Eteghad, S., et al. 2017. PLoS One. 12: e0184122. PMID: 28854284
  3. Matrine Attenuates D-Galactose-Induced Aging-Related Behavior in Mice via Inhibition of Cellular Senescence and Oxidative Stress.  |  Sun, K., et al. 2018. Oxid Med Cell Longev. 2018: 7108604. PMID: 30598725
  4. D-Galactose-induced accelerated aging model: an overview.  |  Azman, KF. and Zakaria, R. 2019. Biogerontology. 20: 763-782. PMID: 31538262
  5. D-galactose-induced aging does not cause further deterioration in brain pathologies and cognitive decline in the obese condition.  |  Shwe, T., et al. 2020. Exp Gerontol. 138: 111001. PMID: 32522583
  6. D-(+)-Galactose-induced aging: A novel experimental model of erectile dysfunction.  |  de Almeida Rezende, MS., et al. 2021. PLoS One. 16: e0249487. PMID: 33857158
  7. D-galactose-induced liver aging model: Its underlying mechanisms and potential therapeutic interventions.  |  Azman, KF., et al. 2021. Exp Gerontol. 150: 111372. PMID: 33905879
  8. An overview of D-galactose utilization through microbial fermentation and enzyme-catalyzed conversion.  |  Chen, Q., et al. 2021. Appl Microbiol Biotechnol. 105: 7161-7170. PMID: 34515844
  9. d-Galactose induced early aging in human erythrocytes: Role of band 3 protein.  |  Remigante, A., et al. 2022. J Cell Physiol. 237: 1586-1596. PMID: 34783011
  10. GalR, GalX and AraR co-regulate d-galactose and l-arabinose utilization in Aspergillus nidulans.  |  Meng, J., et al. 2022. Microb Biotechnol. 15: 1839-1851. PMID: 35213794
  11. Protective effects of cordycepin against d-galactose-induced aging in rats: A view from the heart.  |  Feng, Y. and Huang, Q. 2022. Geriatr Gerontol Int. 22: 433-440. PMID: 35352454
  12. D-galactose-induced cardiac ageing: A review of model establishment and potential interventions.  |  Wang, SS., et al. 2022. J Cell Mol Med. 26: 5335-5359. PMID: 36251271
  13. Chronic D-galactose administration induces natural aging characteristics, in rat's brain and heart.  |  Pantiya, P., et al. 2023. Toxicology. 492: 153553. PMID: 37225035

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D-Galactose, 100 g

sc-202564
100 g
$224.00