ST18 inhibitors represent a class of compounds that target a specific biological molecule known as ST18 (Suppressor of Tumorigenicity 18), which plays a crucial role in various cellular processes. These inhibitors are designed to modulate the activity of ST18 and are of significant interest in the field of molecular biology and pharmacology. ST18 itself is a transcriptional repressor protein that belongs to the BTB/POZ (Broad Complex, Tramtrack, and Bric-a-Brac/Poxvirus, and Zinc finger) domain-containing protein family. This protein family is known for its involvement in the regulation of gene expression, cell cycle progression, and cell differentiation.
ST18 inhibitors work by interfering with the function of ST18, often by binding to it or its associated proteins. This interference can lead to downstream effects on gene expression, which may be relevant in various biological contexts. By modulating the activity of ST18, these inhibitors can influence cellular processes such as proliferation, apoptosis, and differentiation. Researchers have been keenly investigating ST18 inhibitors to gain insights into the fundamental biology of ST18 and its role in disease processes.Understanding the mechanism of action and the structural properties of ST18 inhibitors is crucial for advancing our knowledge of cellular signaling pathways and developing potential interventions.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lopinavir | 192725-17-0 | sc-207831 | 10 mg | $129.00 | 6 | |
Lopinavir is a protease inhibitor that blocks the enzymatic activity of the viral protease, blocking the cleavage of viral polyproteins and viral replication. | ||||||
Ritonavir | 155213-67-5 | sc-208310 | 10 mg | $122.00 | 7 | |
Ritonavir also inhibits the viral protease but is often used in combination with lopinavir to enhance its effectiveness by increasing its plasma half-life. | ||||||
Baricitinib | 1187594-09-7 | sc-364730 sc-364730A | 5 mg 25 mg | $196.00 $651.00 | ||
Baricitinib is a Janus kinase (JAK) inhibitor that modulates the host immune response, reducing inflammation and cytokine storm associated with COVID-19. | ||||||
Arbidol Hydrochloride | 131707-23-8 | sc-210834 | 10 mg | $204.00 | ||
Arbidol Hydrochloride interferes with the fusion of the viral envelope with host cell membranes, blocking viral entry and subsequent infection. | ||||||
Camostat mesylate | 59721-29-8 | sc-203867 sc-203867A sc-203867B sc-203867C sc-203867D sc-203867E | 10 mg 50 mg 500 mg 1 g 10 g 100 g | $42.00 $179.00 $306.00 $612.00 $2040.00 $4386.00 | 5 | |
Camostat inhibits the serine protease TMPRSS2, which is required for SARS-CoV-2 spike protein priming, preventing viral entry into host cells. | ||||||
Ivermectin | 70288-86-7 | sc-203609 sc-203609A | 100 mg 1 g | $56.00 $75.00 | 2 | |
Ivermectin may inhibit the importin α/β1-mediated nuclear import of viral proteins, disrupting viral replication and promoting antiviral effects. | ||||||
Nitazoxanide | 55981-09-4 | sc-212397 | 10 mg | $122.00 | 1 | |
Nitazoxanide interferes with viral maturation by inhibiting viral hemagglutinin-esterase glycoprotein, disrupting the viral life cycle. | ||||||