SR-B1 Activators
The concept of SR-B1 activators is nuanced due to SR-B1's role as a receptor involved in lipid metabolism rather than a traditional protein subject to direct activation. SR-B1, also known as Scavenger Receptor Class B Member 1, plays a crucial role in high-density lipoprotein (HDL) metabolism and cholesterol homeostasis. While there are no specific chemicals classified as direct activators for SR-B1, a range of compounds that influence lipid metabolism can indirectly modulate its functions. The selected chemicals, including Probucol, Gemfibrozil, Ezetimibe, Niacin, Fenofibrate, Oleic Acid, Sitosterol, Lovastatin, Cholestyramine, Omega-3 Fatty Acids, Clofibrate, and Tocotrienols, impact pathways related to lipid metabolism. These compounds have the ability to influence cholesterol levels, cellular lipid transport, and other processes associated with SR-B1. Probucol, for instance, acts as an antioxidant and lipid-lowering agent, impacting cellular cholesterol levels and lipid metabolism pathways. Gemfibrozil can indirectly modulate SR-B1 by affecting lipid metabolism, influencing cholesterol homeostasis and cellular lipid transport.
Ezetimibe inhibits cholesterol absorption, and its impact on cholesterol levels may indirectly affect SR-B1 functions related to lipid transport and metabolism. Niacin, or vitamin B3, modifies cholesterol levels and can influence SR-B1-associated processes related to lipid homeostasis. Fenofibrate, Oleic Acid, Sitosterol, Lovastatin, Cholestyramine, and Clofibrate each contribute to the modulation of lipid metabolism pathways, impacting SR-B1 functions. Omega-3 Fatty Acids, abundant in fish oil, can alter cellular lipid composition, influencing SR-B1 in lipid transport processes. Tocotrienols, a form of vitamin E, have implications in lipid metabolism, influencing SR-B1 functions related to cholesterol homeostasis and cellular lipid transport. While these compounds are not direct activators in the traditional sense, their effects on lipid metabolism pathways can contribute to alterations in SR-B1-associated processes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Gemfibrozil | 25812-30-0 | sc-204764 sc-204764A | 5 g 25 g | $65.00 $262.00 | 2 | |
Gemfibrozil is a fibrate agent in research used to lower cholesterol levels. Its action on lipid metabolism pathways could indirectly modulate SR-B1 functions, influencing cholesterol homeostasis and cellular lipid transport. | ||||||
Ezetimibe | 163222-33-1 | sc-205690 sc-205690A | 25 mg 100 mg | $94.00 $236.00 | 12 | |
Ezetimibe inhibits cholesterol absorption in the intestines. Its impact on cholesterol levels and metabolism may indirectly affect SR-B1, which plays a role in the regulation of cholesterol transport and cellular lipid homeostasis. | ||||||
Nicotinic Acid | 59-67-6 | sc-205768 sc-205768A | 250 g 500 g | $61.00 $122.00 | 1 | |
Niacin, or vitamin B3, can affect lipid metabolism and has been used to modify cholesterol levels. Its influence on cholesterol homeostasis may indirectly impact SR-B1 functions related to lipid transport and metabolism. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $40.00 | 9 | |
Fenofibrate is a fibrate agent in research that can influence lipid metabolism. Its impact on cholesterol levels and related pathways may indirectly modulate SR-B1, contributing to alterations in cellular lipid transport processes. | ||||||
Oleic Acid | 112-80-1 | sc-200797C sc-200797 sc-200797A sc-200797B | 1 g 10 g 100 g 250 g | $36.00 $102.00 $569.00 $1173.00 | 10 | |
Oleic acid is a monounsaturated fatty acid. Changes in fatty acid composition can influence lipid metabolism pathways. Oleic acid may indirectly impact SR-B1 functions related to cellular lipid transport and cholesterol homeostasis. | ||||||
β-Sitosterol | 83-46-5 | sc-204432 sc-204432A | 10 g 25 g | $60.00 $213.00 | 5 | |
Sitosterol is a plant sterol that influences cholesterol absorption. Its effects on cholesterol levels and metabolism could indirectly modulate SR-B1, contributing to alterations in cellular lipid transport and cholesterol homeostasis. | ||||||
Lovastatin | 75330-75-5 | sc-200850 sc-200850A sc-200850B | 5 mg 25 mg 100 mg | $28.00 $88.00 $332.00 | 12 | |
Lovastatin is a statin agent in research that inhibits cholesterol synthesis. Its impact on cholesterol levels and metabolism may indirectly influence SR-B1, which participates in cellular lipid transport and cholesterol homeostasis. | ||||||
CHOLESTYRAMINE RESIN | 11041-12-6 | sc-507509 | 5 g | $210.00 | ||
Cholestyramine is a bile acid sequestrant that can affect cholesterol absorption. Its influence on cholesterol levels and metabolism may indirectly modulate SR-B1, contributing to alterations in cellular lipid transport processes. | ||||||
Clofibrate | 637-07-0 | sc-200721 | 1 g | $32.00 | ||
Clofibrate is a fibrate agent in research that can modulate lipid metabolism. Its impact on cholesterol levels and related pathways may indirectly influence SR-B1, contributing to alterations in cellular lipid transport processes. | ||||||