Date published: 2026-1-9

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SPRR2E Activators

SPRR2E Activators designate a class of chemical compounds recognized for their ability to modulate the activity of the SPRR2E gene. SPRR2E, or Small Proline-Rich Protein 2E, is a gene that encodes a protein involved in various cellular processes, although its precise functions and regulatory mechanisms are still the subject of ongoing research. Activators of SPRR2E are a group of molecules that have the capacity to either enhance the expression of the SPRR2E gene or potentiate its biological activity within a cell. These compounds serve as essential tools for researchers interested in unraveling the biological significance of SPRR2E and its potential involvement in diverse cellular functions.

The exact mechanisms by which SPRR2E activators exert their effects are currently a topic of active scientific investigation. These molecules may act at the transcriptional or post-transcriptional level, potentially influencing the production of SPRR2E protein or modifying its interactions with other cellular components. By manipulating SPRR2E activity, researchers aim to decipher its biological roles, which may encompass roles in cell differentiation, tissue development, or responses to environmental cues. Delving into SPRR2E activators could provide valuable insights into the molecular pathways and cellular processes controlled by this gene, advancing our understanding of its significance in normal cellular physiology and potentially leading to novel insights in fields such as cell biology and genetics.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

As a key regulator of skin differentiation and repair, retinoic acid may upregulate SPRR2E as part of the keratinocyte differentiation process in response to skin damage or stress.

Calcipotriol

112965-21-6sc-203537
sc-203537A
10 mg
50 mg
$203.00
$832.00
4
(1)

A Vitamin D analog that promotes keratinocyte differentiation; it might enhance SPRR2E expression as part of the normal differentiation process or in pathological conditions like psoriasis.

Tazarotene

118292-40-3sc-220193
10 mg
$103.00
(0)

A topical retinoid used in the treatment of psoriasis and acne; it may induce SPRR2E expression by modulating keratinocyte differentiation and skin barrier formation.

(+)-α-Tocopherol

59-02-9sc-214454
sc-214454A
sc-214454B
10 g
25 g
100 g
$43.00
$62.00
$141.00
(1)

As an antioxidant, Vitamin E could help in managing oxidative stress in skin cells, potentially upregulating SPRR2E expression as part of the cellular defense mechanism.

1α,25-Dihydroxyvitamin D3

32222-06-3sc-202877B
sc-202877A
sc-202877C
sc-202877D
sc-202877
50 µg
1 mg
5 mg
10 mg
100 µg
$220.00
$645.00
$1000.00
$1500.00
$440.00
32
(2)

The active form of Vitamin D3, it regulates keratinocyte growth and differentiation, potentially increasing SPRR2E expression in processes related to skin barrier function and repair.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

With anti-inflammatory and antioxidant properties, curcumin might influence SPRR2E expression by modulating cellular stress responses and pathways involved in skin health and disease.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

As a component of green tea with anti-inflammatory properties, EGCG could modulate skin cell responses to environmental stressors, potentially affecting SPRR2E expression.

Hydrocortisone

50-23-7sc-300810
5 g
$102.00
6
(1)

A glucocorticoid that modulates inflammation and cellular stress, hydrocortisone might influence SPRR2E expression in the context of skin inflammation and repair.

Salicylic acid

69-72-7sc-203374
sc-203374A
sc-203374B
100 g
500 g
1 kg
$47.00
$94.00
$119.00
3
(1)

Used in dermatology for its keratolytic effects, salicylic acid might upregulate SPRR2E indirectly by promoting keratinocyte turnover and response to skin barrier disruptions.

Nicotinamide

98-92-0sc-208096
sc-208096A
sc-208096B
sc-208096C
100 g
250 g
1 kg
5 kg
$44.00
$66.00
$204.00
$831.00
6
(1)

As a form of Vitamin B3, niacinamide can improve skin barrier function and might induce SPRR2E expression as part of its effects on skin health, particularly in conditions like atopic dermatitis.