Date published: 2026-2-8

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Sphingomyelin Synthase Antibodies

Santa Cruz Biotechnology delivers a wide array of Sphingomyelin Synthase monoclonal antibodies for research in understanding sphingomyelin synthase's role in cellular processes. Sphingomyelin Synthase Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Sphingomyelin synthase is essential for sphingomyelin synthesis, a key component of cell membranes that plays a significant role in cell signaling, membrane structure, and lipid metabolism. Dysregulation of sphingomyelin synthase has been linked to various diseases, including neurodegenerative disorders and cancer, making it an important target for therapeutic intervention. Understanding sphingomyelin synthase function can provide insights into cellular mechanisms and potential pathways for drug development. Sphingomyelin synthase research has revealed its critical involvement in maintaining cellular homeostasis and membrane organization. Recent studies have highlighted sphingomyelin synthase's role in cellular stress responses and apoptosis regulation. Investigating sphingomyelin synthase activity has uncovered new perspectives on lipid-mediated signaling pathways. Santa Cruz Biotechnology monoclonal antibodies for sphingomyelin synthase research support scientists worldwide in advancing our understanding of cellular biology and disease mechanisms.

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Sphingomyelin Synthase Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SMS1 Antibody (G-8)

sc-133135mouse IgG1 κ21-150 (h)WB, IP, IF, ELISAm, r, h
1
(2)

SMS1 Antibody (E-5)

sc-166436mouse IgG2a κ21-150 (h)WB, IP, IF, ELISAm, r, h
2
(1)

SMS1 Antibody (F-10)

sc-166380mouse IgG2a κ21-150 (h)WB, IP, IF, ELISAm, r, h

new

(1)

SMS2 Antibody (7D10)

sc-293384mouse IgG2a κ2-80 (h)WB, IP, ELISAh
3
(2)

Sphingomyelin Synthase CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SMS1 CRISPR/Cas9 KO Plasmid (h)

sc-403382hGene KnockoutGFP
1
(0)

SMS1 HDR Plasmid (h)

sc-403382-HDRhHomology Directed RepairPuromycin
1
(0)

SMS1 CRISPR/Cas9 KO Plasmid (m)

sc-431565mGene KnockoutGFP
1
(0)

SMS1 HDR Plasmid (m)

sc-431565-HDRmHomology Directed RepairPuromycin
1
(0)

SMS2 CRISPR/Cas9 KO Plasmid (h)

sc-405416hGene KnockoutGFP
1
(0)

SMS2 HDR Plasmid (h)

sc-405416-HDRhHomology Directed RepairPuromycin
1
(0)

SMS2 CRISPR/Cas9 KO Plasmid (m)

sc-428888mGene KnockoutGFP
1
(0)

SMS2 HDR Plasmid (m)

sc-428888-HDRmHomology Directed RepairPuromycin
1
(0)

Sphingomyelin Synthase CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SMS1 CRISPR Activation Plasmid (h)

sc-403382-ACThGene ActivationPuro, Blast, Hygro
1
(0)

Sphingomyelin Synthase siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SMS1 siRNA (h)

sc-44428hGene SilencingN/A0
(0)

SMS1 shRNA Plasmid (h)

sc-44428-SHhGene SilencingPuromycin0
(0)

SMS1 shRNA (h) Lentiviral Particles

sc-44428-VhGene SilencingPuromycin0
(0)

SMS1 siRNA (m)

sc-45308mGene SilencingN/A0
(0)

SMS1 shRNA Plasmid (m)

sc-45308-SHmGene SilencingPuromycin0
(0)

SMS1 shRNA (m) Lentiviral Particles

sc-45308-VmGene SilencingPuromycin0
(0)

SMS2 siRNA (m)

sc-63295mGene SilencingN/A0
(0)

SMS2 shRNA Plasmid (m)

sc-63295-SHmGene SilencingPuromycin0
(0)

SMS2 shRNA (m) Lentiviral Particles

sc-63295-VmGene SilencingPuromycin0
(0)

Sphingomyelin Synthase 2 siRNA (h)

sc-44429hGene SilencingN/A0
(0)

Sphingomyelin Synthase 2 shRNA Plasmid (h)

sc-44429-SHhGene SilencingPuromycin0
(0)

Sphingomyelin Synthase 2 shRNA (h) Lentiviral Particles

sc-44429-VhGene SilencingPuromycin0
(0)