Date published: 2025-9-11

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Sphingolipids

Santa Cruz Biotechnology now offers a broad range of sphingolipids for use in various applications. Sphingolipids are a class of complex lipids containing a sphingoid base backbone, which are essential components of cell membranes and play crucial roles in cellular signaling and structural integrity. These compounds are significant in scientific research due to their involvement in numerous biological processes and their impact on cell function and health. In biochemistry and cell biology, sphingolipids are studied to understand their role in membrane structure, signaling pathways, and their influence on cell behavior, including apoptosis, proliferation, and differentiation. Researchers utilize sphingolipids to investigate mechanisms of diseases associated with lipid metabolism disorders and to explore potential targets for novel strategies, although not in a clinical context. In neuroscience, sphingolipids are crucial for studying the function and organization of the nervous system, given their role in myelin sheath formation and neuron function. Environmental scientists study sphingolipids to understand their role in cellular responses to environmental stressors and their potential as biomarkers for environmental monitoring. Additionally, sphingolipids are employed in the development of advanced materials and nanotechnology, where their unique structural properties can be harnessed for creating biomimetic materials and drug delivery systems. Analytical chemists use sphingolipids in techniques such as mass spectrometry and chromatography to analyze lipid compositions and understand lipidomics, the large-scale study of pathways and networks of cellular lipids in biological systems. The broad applications of sphingolipids in scientific research underscore their importance in advancing our knowledge of fundamental biological processes and driving innovations across multiple disciplines. View detailed information on our available sphingolipids by clicking on the product name.

Items 21 to 30 of 64 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Dihydro-D-erythro-Sphingosine

764-22-7sc-203911
10 mg
$75.00
(0)

Dihydro-D-erythro-Sphingosine is a unique sphingolipid characterized by its dihydro configuration, which impacts its hydrophobicity and molecular interactions. This structural feature enhances its ability to integrate into lipid bilayers, influencing membrane curvature and fluidity. The compound participates in distinct metabolic pathways, contributing to the regulation of cellular processes. Its interactions with proteins and other lipids are pivotal in modulating signaling cascades and maintaining cellular homeostasis.

N-Stearoyl-D-Sphingosine

2304-81-6sc-211176
sc-211176A
1 mg
5 mg
$24.00
$78.00
(0)

N-Stearoyl-D-Sphingosine is a notable sphingolipid distinguished by its long-chain fatty acid moiety, which enhances its hydrophobic interactions within lipid membranes. This structural attribute facilitates the formation of lipid rafts, crucial for cellular signaling and membrane organization. The compound's unique acylation pattern influences its enzymatic pathways, particularly in sphingolipid metabolism, and plays a role in modulating membrane dynamics and cellular responses to environmental stimuli.

Lactosyl Ceramide

4682-48-8sc-204051
1 mg
$238.00
(0)

Lactosyl Ceramide is a unique sphingolipid characterized by its carbohydrate moiety, which promotes specific interactions with membrane proteins and influences cell recognition processes. This glycosphingolipid participates in cellular signaling pathways, particularly in the modulation of immune responses. Its distinct structure allows for the formation of specialized microdomains within membranes, impacting lipid organization and facilitating intercellular communication through glycan-mediated interactions.

N-Oleoyl-D-erythro-sphingosine

5966-28-9sc-205936
sc-205936A
1 mg
5 mg
$290.00
$500.00
(0)

N-Oleoyl-D-erythro-sphingosine is a notable sphingolipid distinguished by its long-chain fatty acid, which enhances membrane fluidity and stability. This compound plays a critical role in lipid rafts, influencing protein localization and signaling pathways. Its unique hydrophobic interactions contribute to the formation of lipid bilayers, while its structural properties facilitate the modulation of cellular responses, impacting processes such as apoptosis and inflammation.

D-erythro-Sphingosine C-20

6918-49-6sc-205282
sc-205282A
500 µg
1 mg
$50.00
$90.00
3
(1)

D-erythro-Sphingosine C-20 is a significant sphingolipid characterized by its long hydrocarbon chain, which contributes to its unique amphipathic nature. This compound is integral to membrane architecture, promoting the formation of lipid domains that influence cellular signaling and membrane dynamics. Its interactions with proteins and other lipids can modulate membrane curvature and fluidity, affecting cellular processes such as endocytosis and signal transduction pathways.

Ganglioside GD1b disodium salt

19553-76-5sc-202622
1 mg
$275.00
6
(1)

Ganglioside GD1b disodium salt is a complex sphingolipid distinguished by its unique carbohydrate moiety, which enhances its ability to interact with specific receptors on cell surfaces. This interaction plays a crucial role in cell recognition and communication. GD1b's structural features facilitate the formation of lipid rafts, influencing membrane organization and stability. Additionally, its presence can modulate neuronal signaling pathways, impacting synaptic plasticity and cellular responses.

L-threo-Sphingosine C-18

25695-95-8sc-205363
sc-205363A
5 mg
10 mg
$200.00
$380.00
(0)

L-threo-Sphingosine C-18 is a bioactive sphingolipid characterized by its long hydrocarbon chain and hydroxyl groups, which contribute to its amphipathic nature. This structure allows it to integrate into lipid bilayers, influencing membrane fluidity and permeability. It participates in the regulation of cellular signaling pathways, particularly in apoptosis and cell growth, by modulating the activity of specific kinases and phosphatases, thereby affecting cellular responses to environmental stimuli.

Nervonic ceramide

54164-50-0sc-202729
5 mg
$207.00
(0)

Nervonic ceramide is a unique sphingolipid distinguished by its long-chain fatty acid composition, which enhances its structural stability within cellular membranes. This ceramide plays a crucial role in lipid rafts, facilitating protein interactions and signaling cascades. Its specific acyl chain length influences membrane dynamics, impacting cellular processes such as differentiation and stress response. Additionally, it participates in the synthesis of complex sphingolipids, contributing to cellular homeostasis.

Ganglioside GQ1b tetrasodium salt

68652-37-9sc-203054
sc-203054A
100 µg
500 µg
$200.00
$570.00
(1)

Ganglioside GQ1b tetrasodium salt is a complex sphingolipid characterized by its unique oligosaccharide structure, which enables specific interactions with cell surface receptors. This ganglioside is integral to neuronal signaling, influencing synaptic transmission and cellular communication. Its distinct carbohydrate moieties facilitate binding to proteins, modulating pathways involved in cell recognition and adhesion. Additionally, GQ1b's presence in lipid membranes affects membrane fluidity and organization, impacting cellular responses to environmental stimuli.

Ganglioside GM1, Asialo

71012-19-6sc-202625
sc-202625A
sc-202625B
1 mg
10 mg
100 mg
$335.00
$2047.00
$15000.00
1
(1)

Ganglioside GM1, Asialo is a notable sphingolipid distinguished by its unique glycan composition, which plays a critical role in cellular interactions. This ganglioside is involved in modulating signal transduction pathways, influencing neuronal plasticity and synaptic function. Its specific carbohydrate chains enhance binding affinity to various proteins, impacting cellular recognition processes. Furthermore, GM1's structural properties contribute to membrane dynamics, affecting lipid raft formation and cellular signaling cascades.