Date published: 2026-4-24

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Nervonic ceramide (CAS 54164-50-0)

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Alternate Names:
N-nervonoyl-D-erythro-sphingosine
Application:
Nervonic ceramide is a naturally occurring ceramide and an integral part of the sphingomyelin cycle
CAS Number:
54164-50-0
Purity:
>98%
Molecular Weight:
648.1
Molecular Formula:
C42H81NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Nervonic ceramide is a synthetic ceramide, a lipid molecule. Among the various types of ceramides, Nervonic ceramide has garnered significant attention in recent years due to its potential applications in the cosmetic industry. The precise mechanism of action for Nervonic ceramide is yet to be fully elucidated. However, it is believed to function by stimulating lipid production in the skin, thereby reinforcing the skin′s barrier function.


Nervonic ceramide (CAS 54164-50-0) References

  1. Sphingomyelinase and ceramide analogs induce contraction and rises in [Ca(2+)](i) in canine cerebral vascular muscle.  |  Zheng, T., et al. 2000. Am J Physiol Heart Circ Physiol. 278: H1421-8. PMID: 10775118
  2. N-Acyl Chain in Ceramide and Sphingomyelin Determines Their Mixing Behavior, Phase State, and Surface Topography in Langmuir Films.  |  Dupuy, FG. and Maggio, B. 2014. J Phys Chem B. 118: 7475-7487. PMID: 24949924
  3. Milk Polar Lipids Affect In Vitro Digestive Lipolysis and Postprandial Lipid Metabolism in Mice.  |  Lecomte, M., et al. 2015. J Nutr. 145: 1770-7. PMID: 26136586
  4. Discovery of Infection Associated Metabolic Markers in Human African Trypanosomiasis.  |  Lamour, SD., et al. 2015. PLoS Negl Trop Dis. 9: e0004200. PMID: 26505639
  5. Development and validation of a high-throughput LC-MS/MS assay for routine measurement of molecular ceramides.  |  Kauhanen, D., et al. 2016. Anal Bioanal Chem. 408: 3475-83. PMID: 26922344
  6. Serum sphingolipid level in psoriatic patients with obesity.  |  Kozłowska, D., et al. 2019. Postepy Dermatol Alergol. 36: 714-721. PMID: 31998000
  7. Landscape of lipidomic metabolites in gut-liver axis of Sprague-Dawley rats after oral exposure to titanium dioxide nanoparticles.  |  Chen, Z., et al. 2022. Part Fibre Toxicol. 19: 53. PMID: 35922847
  8. The Role of Sphingolipids in the Pathogenesis of Psoriasis.  |  Matwiejuk, M., et al. 2022. Metabolites. 12: PMID: 36557209

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Nervonic ceramide, 5 mg

sc-202729
5 mg
$211.00