D-erythro-Sphingosine C-20 (CAS 6918-49-6)

D-erythro-Sphingosine C-20, a naturally derived sphingolipid with an elongated 20-carbon fatty acid chain, is integral to the study of cellular membrane dynamics and lipid signaling pathways. This compound, characterized by its long-chain base, is crucial in the formation of sphingolipids which are vital components of cellular membranes, particularly influencing the structure and fluidity of lipid bilayers. In research, D-erythro-Sphingosine C-20 has been pivotal in elucidating the roles of sphingolipids in modulating membrane-associated events such as protein trafficking, signal transduction, and receptor localization. Its structural properties allow it to integrate into lipid rafts — specialized membrane domains enriched in sphingolipids and cholesterol — thereby affecting the organization and function of these domains. The lipid′s ability to influence calcium ion channels and kinase cascades highlights its role in intracellular signaling mechanisms. Additionally, its involvement in the sphingomyelin cycle, where it acts as a precursor or a degradation product, provides insights into the metabolic pathways of sphingolipids in various cellular processes. Research utilizing D-erythro-Sphingosine C-20 has significantly contributed to understanding the complex interplay between lipid composition, membrane architecture, and cellular function, offering a deeper perspective on how lipid molecules influence cell biology.