SPATA18 Activators represent a unique chemical class distinguished by their ability to upregulate the expression of the SPATA18 protein, a molecular entity playing a crucial role in mitochondrial quality control. This class encompasses a diverse array of compounds, each with distinct chemical structures and properties, yet unified by their common functional impact on SPATA18. The primary characteristic of these activators is their interaction with cellular pathways that lead to the increased expression of SPATA18. This upregulation is particularly significant in the context of mitochondrial health, as SPATA18 is integral to the maintenance and repair of these vital organelles. The mechanisms by which these activators exert their influence are varied, involving complex biochemical pathways, including those related to oxidative stress responses and mitochondrial signaling.
Within the realm of SPATA18 Activators, the compounds exhibit a fascinating diversity in their molecular makeup. Some of these molecules are naturally occurring antioxidants, while others are synthetic entities designed to specifically target the pathways leading to SPATA18 expression. The natural compounds in this class, such as certain polyphenols and vitamins, are notable for their roles in cellular antioxidative defenses. These substances interact with cellular redox states, potentially leading to an upregulation of SPATA18 as part of the cell's response to oxidative challenges. On the other hand, the synthetic members of this class are often more targeted in their action, designed to interact with specific cellular components that influence SPATA18 expression. Regardless of their origin, all SPATA18 Activators share the common feature of influencing the expression of this protein in a manner that is intricately linked with the regulation of mitochondrial function and cellular homeostasis. These activators, through their action on SPATA18, underscore the intricate relationship between cellular signaling pathways and the maintenance of key cellular structures like mitochondria.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
Might upregulate SPATA18 expression as a response to increased oxidative stress, triggering mitochondrial quality control mechanisms. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
May promote SPATA18 expression through its antioxidant effects, enhancing mitochondrial defense against oxidative damage. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Might upregulate SPATA18 as part of its cellular defensive action against oxidative stress, contributing to mitochondrial health. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Could potentially increase SPATA18 expression through its antioxidative and anti-inflammatory mechanisms, supporting mitochondrial function. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $46.00 | 5 | |
May upregulate SPATA18 expression as an antioxidant, aiding in protecting mitochondria from oxidative stress. | ||||||
(+)-α-Tocopherol | 59-02-9 | sc-214454 sc-214454A sc-214454B sc-214454C | 10 g 25 g 100 g 1 kg | $43.00 $62.00 $141.00 $430.00 | ||
Could enhance SPATA18 expression due to its role in neutralizing oxidative stress, beneficial for mitochondrial health. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $71.00 $184.00 | 1 | |
Might induce SPATA18 expression due to its involvement in mitochondrial electron transport and antioxidative defense. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
Potentially increases SPATA18 expression as an antioxidant, aiding in maintaining mitochondrial quality control. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Might stimulate SPATA18 expression due to its antioxidative properties, which are beneficial for mitochondrial function. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Could promote SPATA18 expression as part of its antioxidant action, which supports mitochondrial health and stress response. | ||||||