SPANX-N4 Inhibitors
Inhibitors targeting the function of SPANX-N4 utilize a variety of mechanisms related to the cytoskeleton, specifically affecting the dynamics of microtubules. For instance, certain compounds achieve their inhibitory effects by stabilizing microtubules, preventing them from disassembling, which is a necessary step in various cellular processes. This stabilization could indirectly lead to the inhibition of SPANX-N4 by interfering with microtubule-based functions such as intracellular transport or localization that are crucial for SPANX-N4 activity. Another set of inhibitors binds directly to tubulin, the building block of microtubules, thereby preventing its polymerization into microtubules. This impediment can disrupt the mitotic spindle function and cellular transport mechanisms, which are fundamental for maintaining the proper cellular distribution and function of SPANX-N4.
Other inhibitors act by disrupting microtubule formation or by targeting microtubule-associated motor proteins. By inhibiting the polymerization of tubulin, these compounds can alter the intracellular dynamics that SPANX-N4 may depend on for its localization or function within the cell. Additionally, some inhibitors specifically target the motor proteins that facilitate microtubule-based vesicle transport, consequently hindering the processes essential for the proper functioning of SPANX-N4.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Stabilizes microtubules and prevents their disassembly, which can indirectly inhibit SPANX-N4 by disrupting the microtubule functions that are required for its localization or function. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $102.00 $235.00 $459.00 $1749.00 $2958.00 | 4 | |
Binds to tubulin and inhibits microtubule formation, potentially disrupting the intracellular transport mechanisms necessary for the proper functioning or localization of SPANX-N4. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Destabilizes microtubules, leading to cell cycle arrest, and potentially hindering the processes that are essential for SPANX-N4 activity or distribution within the cell. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Binds to tubulin and inhibits microtubule polymerization, which can interfere with cellular processes vital for the stability and regulation of SPANX-N4. | ||||||
Griseofulvin | 126-07-8 | sc-202171A sc-202171 sc-202171B | 5 mg 25 mg 100 mg | $85.00 $220.00 $598.00 | 4 | |
Disrupts microtubule function by binding to tubulin, potentially altering the intracellular dynamics that SPANX-N4 may rely on for its proper localization or function. | ||||||
Podophyllotoxin | 518-28-5 | sc-204853 | 100 mg | $84.00 | 1 | |
Inhibits tubulin polymerization and therefore could impair cellular mechanisms that are required for the activity or distribution of SPANX-N4. | ||||||
Eribulin | 253128-41-5 | sc-507547 | 5 mg | $865.00 | ||
Inhibits the growth phase of microtubule dynamics, which could affect the cytoskeletal structure necessary for SPANX-N4's proper function or positioning. | ||||||
Monastrol | 254753-54-3 | sc-202710 sc-202710A | 1 mg 5 mg | $120.00 $233.00 | 10 | |
Inhibits the motor protein Eg5, which could disrupt mitotic spindle function and potentially affect processes vital for the activity or localization of SPANX-N4. | ||||||
Combrestatin A4 | 117048-59-6 | sc-204697 sc-204697A | 1 mg 5 mg | $46.00 $81.00 | ||
Binds to tubulin at the colchicine site and inhibits microtubule assembly, which could influence cellular processes essential for SPANX-N4 function or distribution. | ||||||