SPA-L2 Activators represent a specialized class of chemical compounds or molecules that have attracted attention within the realm of molecular biology and cellular research. These activators are designed or discovered with the specific purpose of modulating the activity of the SPA-L2 gene. SPA-L2, or Spindle Assembly-Like 2, is a protein-coding gene present in various organisms, including humans. It plays a role in spindle assembly, a critical process during cell division, where chromosomes are accurately segregated into daughter cells.
The study of SPA-L2 activators holds promise as it enables researchers to investigate the precise role of the SPA-L2 gene in cellular physiology and molecular mechanisms related to cell division. Activation of SPA-L2 can provide valuable insights into its involvement in the intricate process of spindle assembly, ensuring the accurate distribution of genetic material during cell division. By manipulating the activity of SPA-L2 through these activators, scientists aim to gain a deeper understanding of the complex molecular pathways and cellular functions that rely on the gene product, thereby contributing to the broader knowledge of gene regulation and cellular behavior. Consequently, SPA-L2 activators serve as valuable tools for researchers dedicated to unraveling the intricate molecular mechanisms that govern cellular biology and the specific roles played by individual genes in these processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This DNA methyltransferase inhibitor could potentially activate gene expression by causing DNA demethylation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
As a histone deacetylase inhibitor, it may lead to a more open chromatin structure and activate gene transcription. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Known to inhibit mTOR, rapamycin might induce compensatory cellular responses that upregulate certain genes. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
A glucocorticoid that can regulate genes involved in inflammation and immune responses through glucocorticoid receptor activation. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
A PPARγ agonist that could influence gene expression related to metabolism and fat cell differentiation. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
This NF-κB inhibitor could alter the expression of genes involved in the inflammatory response. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
A MAPK pathway inhibitor that could affect genes regulated by ERK/MAPK signaling. | ||||||
Verapamil | 52-53-9 | sc-507373 | 1 g | $374.00 | ||
By blocking calcium channels, verapamil could indirectly affect the expression of calcium-responsive genes. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
As an inducer of oxidative stress, it might activate transcription factors like NRF2, influencing antioxidant response genes. | ||||||
Cobalt(II) chloride | 7646-79-9 | sc-252623 sc-252623A | 5 g 100 g | $64.00 $176.00 | 7 | |
Mimicking hypoxic conditions, it could induce hypoxia-responsive genes via HIF-1α stabilization. | ||||||