Sodium Taurochenodeoxycholate Activators
Sodium Taurochenodeoxycholate plays a crucial role in lipid digestion and absorption in the gastrointestinal tract, with its functional activity being enhanced by several chemical compounds through indirect mechanisms. Ursodeoxycholic Acid, by altering bile acid composition, improves the solubilizing and emulsifying properties of Sodium Taurochenodeoxycholate, thereby boosting its efficiency in fat digestion. Cholestyramine, a bile acid sequestrant, indirectly elevates Sodium Taurochenodeoxycholate levels by promoting increased bile acid synthesis from cholesterol, enhancing lipid processing capabilities. Similarly, Fenofibrate and Ciprofibrate, through PPAR-α activation, modify lipid metabolism and spur bile acid synthesis, thereby augmenting the role of Sodium Taurochenodeoxycholate in emulsifying dietary fats and fat-soluble vitamins. Ezetimibe, by reducing cholesterol absorption, indirectly causes a compensatory rise in bile acid synthesis, enhancing the functionality of Sodium Taurochenodeoxycholate in the enterohepatic circulation.
Furthermore, Obeticholic Acid, acting as an FXR agonist, indirectly bolsters the concentration and activity of Sodium Taurochenodeoxycholate in bile, influencing lipid metabolism. Clofibrate, another PPAR-α agonist, enhances bile acid synthesis, which in turn increases the activity of Sodium Taurochenodeoxycholate in fat digestion. Colesevelam binds to bile acids, including Sodium Taurochenodeoxycholate, in the intestine, leading to increased bile acid synthesis and improved lipid digestion efficiency. Nicotinic Acid, by impacting lipid metabolism, indirectly boosts bile acid synthesis, enhancing Sodium Taurochenodeoxycholate's role in the gastrointestinal system. Gemfibrozil and Atorvastatin, by modulating lipid regulation and cholesterol metabolism, respectively, indirectly increase bile acid synthesis, thereby enhancing the functional role of Sodium Taurochenodeoxycholate in lipid digestion and nutrient absorption. Lastly, Rifampicin, through its induction of cytochrome P450 enzymes, alters bile acid metabolism, indirectly enhancing the activity of Sodium Taurochenodeoxycholate, particularly in fat digestion processes.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ursodeoxycholic acid | 128-13-2 | sc-204935 sc-204935A | 1 g 5 g | $52.00 $131.00 | 4 | |
Ursodeoxycholic Acid, by altering bile acid composition, indirectly enhances the solubilizing and emulsifying properties of Sodium Taurochenodeoxycholate in the intestine, improving its functional activity in fat digestion and absorption. | ||||||
CHOLESTYRAMINE RESIN | 11041-12-6 | sc-507509 | 5 g | $210.00 | ||
Cholestyramine binds bile acids in the intestine, leading to increased synthesis of bile acids from cholesterol. This indirectly enhances the concentration and activity of Sodium Taurochenodeoxycholate in bile, affecting lipid digestion and absorption. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $41.00 | 9 | |
Fenofibrate, by activating PPAR-α, alters lipid metabolism and increases bile acid synthesis. This indirectly enhances the functional role of Sodium Taurochenodeoxycholate in emulsifying dietary fats and fat-soluble vitamins in the intestine. | ||||||
Ezetimibe | 163222-33-1 | sc-205690 sc-205690A | 25 mg 100 mg | $96.00 $241.00 | 12 | |
Ezetimibe, by inhibiting intestinal cholesterol absorption, leads to compensatory increases in bile acid synthesis, indirectly enhancing the functional activity of Sodium Taurochenodeoxycholate in the enterohepatic circulation and lipid digestion. | ||||||
Ciprofibrate | 52214-84-3 | sc-204689 sc-204689A | 25 mg 100 mg | $58.00 $172.00 | ||
Ciprofibrate, by activating PPAR-α, increases bile acid synthesis, indirectly enhancing the activity of Sodium Taurochenodeoxycholate in lipid digestion and nutrient absorption in the gastrointestinal system. | ||||||
Clofibrate | 637-07-0 | sc-200721 | 1 g | $33.00 | ||
As a PPAR-α agonist, Clofibrate indirectly enhances bile acid synthesis, leading to increased functional activity of Sodium Taurochenodeoxycholate in the digestion and absorption of dietary fats and fat-soluble vitamins. | ||||||
Nicotinic Acid | 59-67-6 | sc-205768 sc-205768A | 250 g 500 g | $62.00 $124.00 | 1 | |
Nicotinic Acid, by modulating lipid metabolism, indirectly affects bile acid synthesis, thereby enhancing the functional activity of Sodium Taurochenodeoxycholate in the gastrointestinal tract, particularly in the digestion of fats and fat-soluble vitamins. | ||||||
Gemfibrozil | 25812-30-0 | sc-204764 sc-204764A | 5 g 25 g | $66.00 $267.00 | 2 | |
Gemfibrozil, as a lipid-regulating agent, indirectly increases bile acid synthesis, enhancing the functional role of Sodium Taurochenodeoxycholate in lipid digestion and absorption in the gastrointestinal system. | ||||||
Atorvastatin | 134523-00-5 | sc-337542A sc-337542 | 50 mg 100 mg | $257.00 $505.00 | 9 | |
Atorvastatin, by altering cholesterol metabolism, indirectly influences the synthesis of bile acids, including Sodium Taurochenodeoxycholate, thus enhancing its functional role in lipid digestion and nutrient absorption. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
Rifampicin, by inducing certain cytochrome P450 enzymes, alters bile acid synthesis and metabolism, indirectly enhancing the functional activity of Sodium Taurochenodeoxycholate in the gastrointestinal tract, particularly in fat digestion. | ||||||