SNX3 Activators
The chemical class designated as SNX3 Activators encompasses a diverse array of compounds that indirectly influence the activation of SNX3. These activators primarily operate by modulating various cellular signaling pathways and processes, which intersect with the functional role of SNX3 in endosomal sorting and membrane trafficking. Unlike direct activators, these compounds exert their influence on SNX3 through a cascade of cellular events initiated by their primary action on specific signaling molecules or pathways.
For instance, compounds like Lithium Chloride and Forskolin demonstrate their influence by targeting the Wnt/β-catenin and cAMP pathways, respectively. These pathways, once activated or modulated, have downstream effects that can intersect with the functional dynamics of SNX3. Similarly, inhibitors like U73122 and SB 203580, which target phospholipase C and p38 MAPK, respectively, create a cellular environment where the indirect effects on SNX3's role in endosomal trafficking and protein sorting become pronounced.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride activates the Wnt/β-catenin signaling pathway by inhibiting GSK-3β. This inhibition can lead to the stabilization and accumulation of β-catenin in the cytoplasm and its subsequent translocation to the nucleus. This process may influence SNX3 function by modulating endosomal sorting and trafficking processes associated with the Wnt pathway. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin, through its ability to stimulate adenylate cyclase, increases cAMP levels within cells. Elevated cAMP can modulate various signaling pathways, including those that may intersect with the functional role of SNX3 in membrane trafficking and protein sorting. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB 203580 is a specific inhibitor of p38 MAPK. Inhibition of p38 MAPK can alter the cell’s response to stress and cytokines, potentially impacting pathways that intersect with SNX3's role in the endocytic pathway. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD 98059 is a MEK inhibitor known to block the MAPK/ERK pathway. By influencing this pathway, PD 98059 can alter cellular processes that might interact with SNX3's function in endosomal trafficking and protein sorting. | ||||||
PI-103 | 371935-74-9 | sc-203193 sc-203193A | 1 mg 5 mg | $32.00 $128.00 | 3 | |
PI-103 is a dual inhibitor of PI3K and mTOR. By modulating these pathways, it can influence autophagy and endocytosis processes, potentially affecting SNX3 activity related to membrane trafficking and protein sorting. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR, a central regulator of cell growth and autophagy. This inhibition can influence pathways associated with membrane trafficking and protein sorting, potentially affecting SNX3’s function. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of JNK, which plays a role in stress-activated signaling pathways. Modulating JNK activity can influence various cellular responses, potentially intersecting with SNX3’s role in endosomal sorting. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor. By modulating PI3K/Akt signaling, it can influence cellular processes related to membrane trafficking and protein sorting, where SNX3 is involved. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $103.00 $293.00 $465.00 | 15 | |
Go6983 is a protein kinase C inhibitor. PKC plays a role in various signaling pathways, and its inhibition can influence processes related to membrane dynamics, potentially affecting SNX3’s function. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein, a tyrosine kinase inhibitor, can modulate various signaling pathways by inhibiting tyrosine kinases. This can influence cellular processes where SNX3 plays a role, particularly in endosomal sorting and membrane trafficking. | ||||||