SNIP1 inhibitors belong to a distinctive chemical class that primarily targets the SNIP1 protein, an essential component in various cellular processes. These inhibitors are meticulously designed molecules that bind to the active site of the SNIP1 protein, thereby modulating its function and altering downstream signaling pathways. SNIP1, short for Smad nuclear-interacting protein 1, is involved in crucial intracellular mechanisms, particularly those related to gene expression regulation and cellular responses to environmental cues.
The inhibitors' precise interaction with SNIP1 interrupts its normal interaction with partner molecules, leading to a cascade of effects on cellular processes. By perturbing the function of SNIP1, these inhibitors offer a valuable tool for researchers to probe and better understand intricate cellular pathways and molecular interactions. The development of SNIP1 inhibitors represents a significant advancement in chemical biology and offers a promising means to delve into the intricate web of cellular activities that rely on SNIP1, paving the way for novel insights into basic biological functions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SB-505124 | 694433-59-5 | sc-362794 sc-362794A | 10 mg 50 mg | $327.00 $1377.00 | 2 | |
This is a small molecule inhibitor that targets TGF-beta type I receptor (ALK5) kinase activity, which is involved in TGF-beta signaling. It indirectly affects SNIP1 by inhibiting upstream components of the signaling pathway. | ||||||
TGF-β RI Kinase Inhibitor V | 627536-09-8 | sc-203294 | 2 mg | $88.00 | 3 | |
Another small molecule inhibitor that targets TGF-beta type I receptor kinase activity, potentially affecting SNIP1-mediated signaling. | ||||||
LY2109761 | 700874-71-1 | sc-396262 sc-396262A | 1 mg 5 mg | $89.00 $275.00 | 9 | |
This is a dual TGF-beta receptor I/II kinase inhibitor that can impact TGF-beta signaling, thereby indirectly affecting SNIP1 function. | ||||||
EW-7197 | 1352608-82-2 | sc-507465 | 5 mg | $345.00 | ||
A synthetic small molecule inhibitor that specifically targets SNIP1-Smad interaction, inhibiting TGF-beta signaling at a downstream level. | ||||||
Galloflavin | 568-80-9 | sc-489548 | 10 mg | $380.00 | ||
This compound inhibits SNIP1 expression and thus interferes with TGF-beta signaling pathways. | ||||||
A 83-01 | 909910-43-6 | sc-203791 sc-203791A | 10 mg 50 mg | $202.00 $811.00 | 16 | |
A selective inhibitor of the TGF-beta type I receptor kinase, it can indirectly affect SNIP1-mediated signaling. | ||||||
ALK5 Inhibitor II | 446859-33-2 | sc-221234 sc-221234A sc-221234B sc-221234C sc-221234D sc-221234E sc-221234F | 1 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 g | $77.00 $153.00 $219.00 $663.00 $1248.00 $4382.00 $7850.00 | 8 | |
A pyrazolopyrimidine compound that inhibits TGF-beta receptor I kinase, leading to downstream effects on TGF-beta signaling and potentially SNIP1 function. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
An inhibitor of TGF-beta type I receptor kinase that can impact TGF-beta signaling pathways, potentially affecting SNIP1-mediated functions. | ||||||
Pirfenidone | 53179-13-8 | sc-203663 sc-203663A | 10 mg 50 mg | $102.00 $416.00 | 6 | |
While primarily known for its anti-fibrotic properties, pirfenidone might indirectly influence SNIP1 through its effects on TGF-beta signaling. | ||||||