Slfn1," or Schlafen family member 1, is a gene that plays a role in the immune response and cellular growth regulation. It belongs to the Schlafen (Slfn) gene family, which is known for its involvement in the regulation of cell proliferation, differentiation, and immune system functions.The Schlafen genes are characterized by their expression in response to various immunological stimuli. Specifically, Slfn1 has been observed to be upregulated in response to interferons, which are cytokines that play a critical role in the immune response, particularly in antiviral defense. This upregulation suggests that Slfn1 is involved in the cellular response to viral infections.
The protein encoded by the Slfn1 gene has been implicated in the regulation of cell growth and the cell cycle. This regulation is crucial for maintaining normal cellular functions and for preventing abnormal cell proliferation, which is a hallmark of cancer. Research has indicated that Slfn1 may have a role in inhibiting the growth of certain types of cancer cells, though the exact mechanisms are not fully understood.
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| Nom du produit | CAS # | Ref. Catalogue | Quantité | Prix HT | CITATIONS | Classement |
|---|---|---|---|---|---|---|
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Un immunosuppresseur qui peut affecter la fonction des cellules immunitaires, ce qui pourrait avoir un impact sur la SLFN1. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
La rapamycine, un inhibiteur de mTOR, peut influencer la SLFN1 en affectant la prolifération et la survie cellulaires. | ||||||
Ruxolitinib | 941678-49-5 | sc-364729 sc-364729A sc-364729A-CW | 5 mg 25 mg 25 mg | $246.00 $490.00 $536.00 | 16 | |
Les inhibiteurs de JAK peuvent moduler la signalisation des cytokines, ce qui pourrait avoir un impact sur le rôle de la SLFN1 dans la fonction des cellules immunitaires. | ||||||
Azathioprine | 446-86-6 | sc-210853D sc-210853 sc-210853A sc-210853B sc-210853C | 500 mg 1 g 2 g 5 g 10 g | $199.00 $173.00 $342.00 $495.00 $690.00 | 1 | |
Médicament immunosuppresseur qui pourrait influencer indirectement l'activité de la SLFN1 par ses effets sur les cellules immunitaires. | ||||||
Prednisone | 53-03-2 | sc-205816 sc-205816A sc-205816B | 1 g 5 g 25 g | $41.00 $133.00 $663.00 | 2 | |
En tant que corticostéroïde, la prednisone affecte les réponses immunitaires, ce qui pourrait indirectement influencer la SLFN1. | ||||||
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $109.00 $350.00 | 8 | |
Connue pour ses effets immunomodulateurs, la thalidomide pourrait affecter indirectement l'activité de la SLFN1. | ||||||
Mycophenolate mofetil | 128794-94-5 | sc-200971 sc-200971A | 20 mg 100 mg | $36.00 $107.00 | 1 | |
Un immunosuppresseur qui pourrait avoir une influence indirecte sur la SLFN1 par son action sur les lymphocytes. | ||||||