Slfn1 Activators
Slfn1," or Schlafen family member 1, is a gene that plays a role in the immune response and cellular growth regulation. It belongs to the Schlafen (Slfn) gene family, which is known for its involvement in the regulation of cell proliferation, differentiation, and immune system functions.The Schlafen genes are characterized by their expression in response to various immunological stimuli. Specifically, Slfn1 has been observed to be upregulated in response to interferons, which are cytokines that play a critical role in the immune response, particularly in antiviral defense. This upregulation suggests that Slfn1 is involved in the cellular response to viral infections.
The protein encoded by the Slfn1 gene has been implicated in the regulation of cell growth and the cell cycle. This regulation is crucial for maintaining normal cellular functions and for preventing abnormal cell proliferation, which is a hallmark of cancer. Research has indicated that Slfn1 may have a role in inhibiting the growth of certain types of cancer cells, though the exact mechanisms are not fully understood.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
An immunosuppressant that can affect immune cell function, potentially impacting SLFN1. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, Rapamycin may influence SLFN1 by affecting cellular proliferation and survival. | ||||||
Ruxolitinib | 941678-49-5 | sc-364729 sc-364729A sc-364729A-CW | 5 mg 25 mg 25 mg | $246.00 $490.00 $536.00 | 16 | |
JAK inhibitors can modulate cytokine signaling, potentially impacting SLFN1's role in immune cell function. | ||||||
Azathioprine | 446-86-6 | sc-210853D sc-210853 sc-210853A sc-210853B sc-210853C | 500 mg 1 g 2 g 5 g 10 g | $199.00 $173.00 $342.00 $495.00 $690.00 | 1 | |
An immunosuppressive drug that could indirectly influence SLFN1 activity through its effects on immune cells. | ||||||
Prednisone | 53-03-2 | sc-205816 sc-205816A sc-205816B | 1 g 5 g 25 g | $41.00 $133.00 $663.00 | 2 | |
As a corticosteroid, Prednisone affects immune responses, which could indirectly influence SLFN1. | ||||||
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $109.00 $350.00 | 8 | |
Known for its immunomodulatory effects, Thalidomide might indirectly affect SLFN1 activity. | ||||||
Mycophenolate mofetil | 128794-94-5 | sc-200971 sc-200971A | 20 mg 100 mg | $36.00 $107.00 | 1 | |
An immunosuppressant that might have an indirect influence on SLFN1 through its action on lymphocytes. | ||||||