SLC46A3, also known as solute carrier family 46 member 3, is a protein encoded by the SLC46A3 gene in humans. This protein is a member of the solute carrier (SLC) superfamily, which comprises membrane-bound transporters responsible for the movement of various molecules across cellular and organelle membranes.The SLC46 family, to which SLC46A3 belongs, is less thoroughly characterized than other SLC families, and the specific substrates and physiological functions of SLC46A3 are not well-defined. Members of the SLC46 family are thought to be involved in the transport of certain organic molecules; however, the precise role of SLC46A3 in these processes remains to be elucidated.
Given the general function of solute carriers, it is hypothesized that SLC46A3 may play a role in the cellular uptake or efflux of specific substrates, potentially contributing to the homeostasis of small molecules within cells and tissues. The expression pattern of SLC46A3 across different tissue types and its regulation under physiological or pathological conditions could provide insights into its biological significance.The study of SLC46A3 is important as it may reveal new aspects of cellular transport mechanisms and contribute to a deeper understanding of cellular nutrition, detoxification, and signaling. Moreover, alterations in the function or expression of solute carriers like SLC46A3 can be associated with various diseases, including metabolic disorders, cancer, and neurological conditions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylyl cyclase, potentially influencing membrane transport mechanisms relevant to SLC46A3. | ||||||
Ouabain-d3 (Major) | sc-478417 | 1 mg | $516.00 | |||
A Na⁺/K⁺-ATPase inhibitor, which might indirectly affect transport processes related to SLC46A3. | ||||||
12β-Hydroxydigitoxin | 20830-75-5 | sc-213604 sc-213604A | 1 g 5 g | $143.00 $694.00 | ||
Another Na⁺/K⁺-ATPase inhibitor, could indirectly modulate cellular transport mechanisms involving SLC46A3. | ||||||
Amiloride • HCl | 2016-88-8 | sc-3578 sc-3578A | 25 mg 100 mg | $22.00 $57.00 | 6 | |
A diuretic that inhibits sodium channels, potentially affecting sodium transport processes relevant to SLC46A3. | ||||||
Furosemide | 54-31-9 | sc-203961 | 50 mg | $41.00 | ||
A loop diuretic, affects ion transport and could indirectly impact mechanisms involving SLC46A3. | ||||||
Verapamil | 52-53-9 | sc-507373 | 1 g | $374.00 | ||
A calcium channel blocker, might influence calcium transport and indirectly affect SLC46A3-related pathways. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $59.00 $173.00 | 15 | |
Another calcium channel blocker, potentially affecting transport mechanisms related to SLC46A3. | ||||||
Probenecid | 57-66-9 | sc-202773 sc-202773A sc-202773B sc-202773C | 1 g 5 g 25 g 100 g | $28.00 $39.00 $100.00 $277.00 | 28 | |
Inhibits organic anion transporters and could indirectly affect transport processes related to SLC46A3. | ||||||
Cimetidine | 51481-61-9 | sc-202996 sc-202996A | 5 g 10 g | $62.00 $86.00 | 1 | |
Inhibits certain drug transporters, potentially impacting transport pathways involving SLC46A3. | ||||||
Quinidine | 56-54-2 | sc-212614 | 10 g | $104.00 | 3 | |
Affects multiple ion channels and transporters, potentially influencing pathways related to SLC46A3. | ||||||