Date published: 2026-2-14

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SLC12A8 Inhibitors

SLC12A8 Inhibitors are a chemical class of compounds that have been under scientific investigation for their potential to selectively modulate the activity of Solute Carrier Family 12 Member 8 (SLC12A8). SLC12A8 is a member of the SLC12 family of cation-chloride cotransporters, which play a critical role in mediating the transport of ions, including sodium and chloride, across cell membranes. The chemical class of SLC12A8 Inhibitors is meticulously designed to interact with specific regions or binding sites within the SLC12A8 protein. By doing so, these inhibitors aim to influence its functional activity, which may involve the modulation of ion transport across cell membranes, particularly with regard to sodium and chloride ions. Exploring SLC12A8 Inhibitors is of significant interest in the field of cell biology and physiology, as they offer the opportunity to investigate the functional implications of SLC12A8 in cellular ion homeostasis and other cellular processes.

By deciphering the impact of these inhibitors on SLC12A8 activity, researchers aim to shed light on the broader context of cellular signaling pathways and networks involving SLC12A8, potentially unraveling novel regulatory mechanisms and cellular functions. The study of SLC12A8 Inhibitors holds the potential to advance our understanding of cellular ion transport and its role in various physiological and pathophysiological conditions. Additionally, investigating the effects of these inhibitors may offer insights into the broader cellular processes in which SLC12A8 is involved, contributing to the advancement of cellular and molecular biology research. However, it is essential to underscore that the field of SLC12A8 Inhibitors is continuously evolving, and comprehensive investigations are necessary to fully elucidate the precise mechanisms of action and potential selectivity of these compounds for SLC12A8. As with any active area of research, continued exploration of SLC12A8 Inhibitors holds promise in advancing our understanding of the functions and implications of the SLC12A8 protein, potentially leading to novel discoveries and future research avenues in cell biology and related disciplines.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Furosemide

54-31-9sc-203961
50 mg
$41.00
(1)

A loop diuretic that inhibits NKCC2.

Hydrochlorothiazide

58-93-5sc-207738
sc-207738A
sc-207738B
sc-207738C
sc-207738D
5 g
25 g
50 g
100 g
250 g
$55.00
$240.00
$333.00
$562.00
$988.00
(0)

A thiazide diuretic.

Indapamide

26807-65-8sc-204777
sc-204777A
250 mg
1 g
$46.00
$64.00
(0)

A thiazide-like diuretic.

Chlorthalidone

77-36-1sc-207427
25 mg
$243.00
1
(1)

A thiazide-like diuretic.

Bumetanide (Ro 10-6338)

28395-03-1sc-200727
sc-200727A
1 g
5 g
$109.00
$228.00
9
(1)

Another loop diuretic that inhibits NKCC2.

Torsemide

56211-40-6sc-213059
10 mg
$260.00
(0)

Torsemide is an inhibitor of NKCC

Ethacrynic acid

58-54-8sc-257424
sc-257424A
1 g
5 g
$90.00
$300.00
5
(1)

A loop diuretic that inhibits NKCC2.

Metolazone

17560-51-9sc-211900
100 mg
$228.00
(1)

A thiazide-like diuretic often used in combination with other diuretics.