Torsemide (CAS 56211-40-6)
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Torsemide is widely utilized in research focused on understanding diuretic-induced diuresis and electrolyte balance in vitro. Its role in inhibiting the Na+/K+/2Cl- cotransporter in the thick ascending limb of the loop of Henle is of particular interest, as this mechanism is central to its diuretic action. Researchers also employ Torsemide to study its effects on renal hemodynamics, which can provide insights into kidney function and fluid management in states of altered renal performance. Additionally, Torsemide is used in environmental studies, like those examining the impact of diuretics on aquatic life, since it can be found as a contaminant in wastewater. Within agricultural research, its effects on plants when present in irrigated water is another area of study, given the importance of understanding how human pharmaceuticals can influence plant growth and soil chemistry.
Torsemide (CAS 56211-40-6) References
- Torsemide-induced pseudoporphyria. | Pérez-Bustillo, A., et al. 2008. Arch Dermatol. 144: 812-3. PMID: 18559783
- A comprehensive review of the loop diuretics: should furosemide be first line? | Wargo, KA. and Banta, WM. 2009. Ann Pharmacother. 43: 1836-47. PMID: 19843838
- Should torsemide be the loop diuretic of choice in systolic heart failure? | DiNicolantonio, JJ. 2012. Future Cardiol. 8: 707-28. PMID: 23013124
- Comparing torsemide versus furosemide in patients with heart failure: A meta-analysis. | Kido, K., et al. 2019. J Am Pharm Assoc (2003). 59: 432-438. PMID: 30846351
- Torsemide versus furosemide after acute decompensated heart failure: a retrospective observational study. | Rahhal, A., et al. 2019. BMC Cardiovasc Disord. 19: 127. PMID: 31138146
- Meta-Analysis Comparing Torsemide Versus Furosemide in Patients With Heart Failure. | Abraham, B., et al. 2020. Am J Cardiol. 125: 92-99. PMID: 31699358
- Pragmatic Design of Randomized Clinical Trials for Heart Failure: Rationale and Design of the TRANSFORM-HF Trial. | Greene, SJ., et al. 2021. JACC Heart Fail. 9: 325-335. PMID: 33714745
- An evaluation of torsemide in patients with heart failure and renal disease. | Peters, AE., et al. 2022. Expert Rev Cardiovasc Ther. 20: 5-11. PMID: 34936522
- Torsemide comparison with furosemide for management of heart failure (TRANSFORM-HF) trial. | Verbrugge, FH. and Menon, V. 2022. Eur Heart J Acute Cardiovasc Care. 11: 931-932. PMID: 36351030
- Torsemide Pharmacometrics in Healthy Adult Populations Including CYP2C9 Genetic Polymorphisms and Various Patient Groups through Physiologically Based Pharmacokinetic-Pharmacodynamic Modeling. | Jeong, SH., et al. 2022. Pharmaceutics. 14: PMID: 36559213
- Heart Failure With Preserved Ejection Fraction: A Review. | Redfield, MM. and Borlaug, BA. 2023. JAMA. 329: 827-838. PMID: 36917048
- Torsemide: a pyridine-sulfonylurea loop diuretic. | Blose, JS., et al. 1995. Ann Pharmacother. 29: 396-402. PMID: 7633019
- Torsemide: a new loop diuretic. | Fowler, SF. and Murray, KM. 1995. Am J Health Syst Pharm. 52: 1771-80; quiz 1814-5. PMID: 8528833
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Torsemide, 10 mg | sc-213059 | 10 mg | $260.00 |