Date published: 2026-4-24

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SH2D Antibodies

Santa Cruz Biotechnology features a diverse variety of SH2D monoclonal antibodies for studying SH2 domain-containing protein, which plays a critical role in immune signaling pathways. SH2D monoclonal antibodies are compatible with multiple research techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The SH2 domain is essential for mediating protein-protein interactions and is involved in the regulation of cellular processes such as proliferation, differentiation, and apoptosis. Understanding SH2D protein function is crucial for elucidating its role in immune responses and implications in diseases, including immunodeficiencies and certain cancers. SH2D monoclonal antibodies enable researchers to explore protein expression patterns in various cell types and tissues. Investigating SH2D protein interactions helps reveal the complex networks of cellular signaling pathways. Advanced research techniques using SH2D monoclonal antibodies support the identification of potential therapeutic targets. Santa Cruz Biotechnology monoclonal antibodies for SH2D research contribute to advancing our understanding of immune system regulation and disease treatment strategies.

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SH2D Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SH2D1A Antibody (A-8)

sc-398118mouse IgG1 λFL (h)WB, IP, IF, ELISAm, r, h

new

(1)

SH2D1A Antibody (1D12)

sc-53859rat IgG2aFL (h)WB, IP, FCM, ELISAh
3
(1)

SH2D4A Antibody (F-5)

sc-514170mouse IgG2a κ113-165 (h)WB, IP, IF, ELISAh
1
(2)

SH2D4A Antibody (63-J)

sc-100288mouse IgG2a κ239-338 (h)WB, IP, IF, IHC(P), ELISAh

new

(2)

SH2D CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SH2D1A Double Nickase Plasmid (h)

sc-404747-NIChGene KnockoutPuromycin0
(0)

SH2D1A Double Nickase Plasmid (h2)

sc-404747-NIC-2hGene KnockoutPuromycin0
(0)

SH2D1A CRISPR/Cas9 KO Plasmid (m)

sc-422910mGene KnockoutGFP0
(0)

SH2D4A CRISPR/Cas9 KO Plasmid (h)

sc-406597hGene KnockoutGFP0
(0)

SH2D4A HDR Plasmid (h)

sc-406597-HDRhHomology Directed RepairPuromycin0
(0)

SH2D CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SH2D1A CRISPR Activation Plasmid (h)

sc-404747-ACThGene ActivationPuro, Blast, Hygro0
(0)

SH2D siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SH2D1A siRNA (h)

sc-40819hGene SilencingN/A0
(0)

SH2D1A shRNA Plasmid (h)

sc-40819-SHhGene SilencingPuromycin0
(0)

SH2D1A shRNA (h) Lentiviral Particles

sc-40819-VhGene SilencingPuromycin0
(0)

SH2D1A siRNA (m)

sc-40820mGene SilencingN/A0
(0)

SH2D1A shRNA Plasmid (m)

sc-40820-SHmGene SilencingPuromycin0
(0)

SH2D1A shRNA (m) Lentiviral Particles

sc-40820-VmGene SilencingPuromycin0
(0)

SH2D3A siRNA (h)

sc-97232hGene SilencingN/A0
(0)

SH2D3A shRNA Plasmid (h)

sc-97232-SHhGene SilencingPuromycin0
(0)

SH2D3A shRNA (h) Lentiviral Particles

sc-97232-VhGene SilencingPuromycin0
(0)

SH2D4A siRNA (h)

sc-77685hGene SilencingN/A0
(0)

SH2D4A shRNA Plasmid (h)

sc-77685-SHhGene SilencingPuromycin0
(0)

SH2D4A shRNA (h) Lentiviral Particles

sc-77685-VhGene SilencingPuromycin0
(0)

SH2D4B siRNA (h)

sc-90409hGene SilencingN/A0
(0)

SH2D4B shRNA Plasmid (h)

sc-90409-SHhGene SilencingPuromycin0
(0)

SH2D4B shRNA (h) Lentiviral Particles

sc-90409-VhGene SilencingPuromycin0
(0)

SH2D5 siRNA (h)

sc-78756hGene SilencingN/A0
(0)

SH2D5 shRNA Plasmid (h)

sc-78756-SHhGene SilencingPuromycin0
(0)

SH2D5 shRNA (h) Lentiviral Particles

sc-78756-VhGene SilencingPuromycin0
(0)

SH2D5 siRNA (m)

sc-153431mGene SilencingN/A0
(0)

SH2D5 shRNA Plasmid (m)

sc-153431-SHmGene SilencingPuromycin0
(0)

SH2D5 shRNA (m) Lentiviral Particles

sc-153431-VmGene SilencingPuromycin0
(0)

SH2D6 siRNA (h)

sc-94359hGene SilencingN/A0
(0)

SH2D6 shRNA Plasmid (h)

sc-94359-SHhGene SilencingPuromycin0
(0)

SH2D6 shRNA (h) Lentiviral Particles

sc-94359-VhGene SilencingPuromycin0
(0)

SH2D7 siRNA (h)

sc-90126hGene SilencingN/A0
(0)

SH2D7 shRNA Plasmid (h)

sc-90126-SHhGene SilencingPuromycin0
(0)

SH2D7 shRNA (h) Lentiviral Particles

sc-90126-VhGene SilencingPuromycin0
(0)