SGLT-4 Activators
SGLT-4 activators belong to a specialized class of chemical compounds that have garnered attention in the field of molecular biology and genetics. These compounds are meticulously designed to modulate the activity of SGLT-4, a protein-coding gene with a role in various cellular processes, particularly in the context of glucose transport and regulation. SGLT-4, or Sodium-Glucose Cotransporter 4, is a member of the SGLT family of transporters, known for their involvement in the uptake of glucose and related sugars across cell membranes. SGLT-4 activators function by targeting specific regulatory elements within the SGLT-4 gene, often located in promoter or enhancer regions, with the primary aim of enhancing its transcription and subsequent translation into functional protein products.
The mechanisms through which SGLT-4 activators exert their effects may vary, but their core purpose is to act as molecular switches, amplifying the activity of SGLT-4. Researchers are continually exploring the potential applications and implications of SGLT-4 activation, aiming to deepen our understanding of how this gene contributes to cellular processes, particularly within the context of glucose transport and regulation. This class of compounds holds promise for advancing our knowledge of gene regulation, particularly within the realm of glucose transporters, offering insights into the intricate mechanisms that underlie glucose uptake and the role of SGLT-4 in various biological contexts. SGLT-4 activators serve as valuable tools in the ongoing exploration of molecular biology, providing opportunities to uncover the complex roles that SGLT-4 plays in cellular processes and its potential contributions to glucose homeostasis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Metformin can activate AMP-activated protein kinase (AMPK), leading to changes in gene expression and potentially affecting SGLT-4 expression. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
As a PPAR-γ agonist, rosiglitazone can modulate transcription of genes involved in glucose metabolism, which may include SGLT-4. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
Similar to rosiglitazone, pioglitazone acts on PPAR-γ and could influence the expression of genes in glucose homeostasis, potentially SGLT-4. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $40.00 | 9 | |
Fenofibrate, a PPAR-α agonist, can affect gene expression related to lipid and glucose metabolism, with possible effects on SGLT-4 expression. | ||||||
D(+)Glucose, Anhydrous | 50-99-7 | sc-211203 sc-211203B sc-211203A | 250 g 5 kg 1 kg | $37.00 $194.00 $64.00 | 5 | |
High glucose levels can lead to transcriptional changes that might upregulate glucose transporters like SGLT-4 as a compensatory mechanism. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Insulin signaling can modulate the expression of several genes, including those for glucose transporters, potentially influencing SGLT-4 levels. | ||||||
Chromium Picolinate | 14639-25-9 | sc-204685 sc-204685A | 5 g 25 g | $214.00 $667.00 | 1 | |
Chromium picolinate is thought to enhance insulin sensitivity, which could indirectly modify the expression of glucose transporters like SGLT-4. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $90.00 | 1 | |
Berberine may activate AMPK, leading to downstream effects on metabolic gene expression which could include modulation of SGLT-4 expression. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
Known to influence glucose metabolism, alpha-lipoic acid might affect the expression of glucose transporters through its antioxidative properties. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
This active form of vitamin D can modulate gene expression via the vitamin D receptor, possibly affecting genes like SGLT-4. | ||||||