Date published: 2026-1-11

1-800-457-3801

SCBT Portrait Logo
Seach Input

SAP 97 Inhibitors

SAP 97 inhibitors, also known as DLG1-associated protein 1 (DLGAP1) inhibitors, are a class of small molecules that target a specific protein called SAP 97. SAP 97, or synapse-associated protein 97, is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, which are crucial for the organization and regulation of synaptic junctions in the nervous system. These inhibitors are designed to modulate the activity of SAP 97 by binding to it and interfering with its normal functions. SAP 97 plays a pivotal role in synaptic plasticity, which is the ability of synapses (the connections between nerve cells) to change and adapt in response to neural activity. Specifically, it is involved in the regulation of glutamate receptor trafficking and clustering at the synapse. By inhibiting SAP 97, these small molecules have the ability to influence the strength and stability of synaptic connections, which could have profound effects on neuronal communication and signal processing. This class of inhibitors may be valuable tools for researchers studying the molecular mechanisms underlying synaptic plasticity and its role in various neurological processes.

Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Fluorouracil

51-21-8sc-29060
sc-29060A
1 g
5 g
$37.00
$152.00
11
(1)

5-Fluorouracil is a pyrimidine analog that can incorporate into RNA and inhibit thymidylate synthase, potentially affecting the transcription and stability of various RNAs, including those encoding SAP 97.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$41.00
$84.00
$275.00
127
(6)

Cycloheximide inhibits protein synthesis at the translation level, which could lead to reduced levels of SAP 97, as it hampers the overall protein production in cells.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Actinomycin D binds to DNA and inhibits RNA synthesis. This interaction may prevent the transcription of the SAP 97 gene, thereby reducing its expression.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Rapamycin inhibits the mTOR pathway, which is involved in protein synthesis. This inhibition can result in decreased expression of proteins, including SAP 97.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$60.00
$265.00
$1000.00
163
(3)

MG-132 is a proteasome inhibitor that prevents the degradation of ubiquitinated proteins, potentially leading to altered protein turnover and expression, including that of SAP 97.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

Trichostatin A is a histone deacetylase inhibitor that can alter chromatin structure and affect gene expression, possibly leading to changes in SAP 97 levels.

Valproic Acid

99-66-1sc-213144
10 g
$87.00
9
(1)

Valproic Acid has histone deacetylase inhibitory activity, potentially modifying chromatin and affecting the transcription of various genes, including SAP 97.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium Chloride affects various signaling pathways, including the Wnt pathway, and may influence the expression of numerous genes, including that of SAP 97.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$135.00
$1085.00
115
(2)

Bortezomib is a proteasome inhibitor, affecting protein turnover. This action can alter the levels of various proteins, including SAP 97.

Chloroquine

54-05-7sc-507304
250 mg
$69.00
2
(0)

Chloroquine can affect lysosomal function and autophagy, potentially influencing the degradation and expression of various proteins, including SAP 97.