SAP 155 Activators
The chemical class of SF3B1 Activators includes compounds that can indirectly influence the activity of SF3B1 through their effects on splicing factors, RNA processing, and related cellular signaling pathways. These compounds do not directly activate SF3B1; instead, they modulate cellular environments or pathways that could impact SF3B1's functional role in RNA splicing.
Compounds like Pladienolide B, Spliceostatin A, Meayamycin, Sudemycin D6, and E7107 target components of the spliceosome complex, potentially affecting SF3B1's activity in RNA splicing. Isoginkgetin and histone deacetylase inhibitors like Trichostatin A, Vorinostat, and Romidepsin may affect gene expression patterns, potentially impacting the splicing activities of SF3B1. Proteasome inhibitors like Bortezomib and MG-132 could indirectly influence the dynamics of splicing factors, including SF3B1, by affecting protein turnover and cellular stress responses.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Pladienolide B | 445493-23-2 | sc-391691 sc-391691B sc-391691A sc-391691C sc-391691D sc-391691E | 0.5 mg 10 mg 20 mg 50 mg 100 mg 5 mg | $299.00 $5699.00 $11099.00 $25500.00 $66300.00 $2875.00 | 63 | |
Inhibits splicing by targeting the SF3B complex, potentially influencing SF3B1's function. | ||||||
Spliceostatin A | 391611-36-2 | sc-507481 | 1 mg | $1800.00 | ||
Another inhibitor of the SF3B complex, could indirectly affect SF3B1's activity in splicing. | ||||||
Isoginkgetin | 548-19-6 | sc-507430 | 5 mg | $225.00 | ||
A biflavonoid that inhibits mRNA splicing, potentially impacting SF3B1's function. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor, may affect gene expression and potentially splicing processes involving SF3B1. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Another histone deacetylase inhibitor, could influence RNA splicing activities of SF3B1. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
A proteasome inhibitor, might indirectly affect splicing factor dynamics and SF3B1's function. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
Another proteasome inhibitor, could impact spliceosome components including SF3B1. | ||||||
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $218.00 $634.00 | 1 | |
A histone deacetylase inhibitor, may influence chromatin structure and thereby affect splicing and SF3B1. | ||||||