Date published: 2025-10-15

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Sad-1 Inhibitors

Sad-1, identified predominantly in the model organism Caenorhabditis elegans, is implicated in various neuronal processes, including synaptic transmission and development. Within the intricacies of the neural system, maintaining proper synaptic function is imperative to ensure efficient communication between nerve cells. Synaptic transmission is facilitated when an electrical impulse or action potential reaches the synapse's end, leading to the release of neurotransmitters. These chemical messengers traverse the synaptic cleft and bind to receptors on the adjacent neuron, thus transmitting the signal. Proteins like Sad-1 are essential in ensuring that synapses form correctly and function properly, allowing for the precise transmission of signals across neurons.

Sad-1 Inhibitors encompass a class of compounds meticulously designed to target and impede the Sad-1 protein's function. The modulation of Sad-1 by these inhibitors can profoundly influence synaptic development and transmission. If the activity of Sad-1 is compromised by these inhibitors, it might result in aberrant synaptic connections or altered synaptic function, leading to disruptions in the communication pathways of the neural network where Sad-1 is operative. Grasping the dynamics of Sad-1 inhibitors can shed light on the multifaceted processes underpinning synaptic formation and function. A thorough exploration into the impacts of these inhibitors can offer deep insights into the regulatory mechanisms that orchestrate the harmonious and efficient transmission of signals in the nervous system, highlighting the pivotal role of proteins like Sad-1 in the grand scheme of neuronal communication.

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Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$150.00
$388.00
113
(4)

A broad-spectrum kinase inhibitor that might influence the kinase activity of Sad-1.

K-252a

99533-80-9sc-200517
sc-200517B
sc-200517A
100 µg
500 µg
1 mg
$126.00
$210.00
$488.00
19
(2)

Related to staurosporine, this inhibitor targets a variety of kinases and could potentially affect Sad-1.

Lavendustin A

125697-92-9sc-200539
sc-200539A
1 mg
5 mg
$116.00
$456.00
(1)

A tyrosine kinase inhibitor that might interact with the tyrosine kinase domain of Sad-1, if present.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

A selective inhibitor of MEK, which is upstream of MAPK/ERK signaling, could indirectly influence Sad-1.

Dasatinib

302962-49-8sc-358114
sc-358114A
25 mg
1 g
$47.00
$145.00
51
(1)

A multi-target kinase inhibitor that may interact with kinases related to Sad-1.

Sunitinib, Free Base

557795-19-4sc-396319
sc-396319A
500 mg
5 g
$150.00
$920.00
5
(0)

Known to target multiple receptor tyrosine kinases, it could potentially influence Sad-1.

Imatinib mesylate

220127-57-1sc-202180
sc-202180A
25 mg
100 mg
$44.00
$109.00
61
(1)

As a tyrosine kinase inhibitor, it might affect tyrosine kinase domains in Sad-1.

Vandetanib

443913-73-3sc-220364
sc-220364A
5 mg
50 mg
$167.00
$1353.00
(1)

Targets EGFR and VEGFR signaling. If Sad-1 is related to these pathways, it might be influenced.

Nilotinib

641571-10-0sc-202245
sc-202245A
10 mg
25 mg
$205.00
$405.00
9
(1)

Another tyrosine kinase inhibitor that might interact with kinase domains in Sad-1.

Pazopanib

444731-52-6sc-396318
sc-396318A
25 mg
50 mg
$127.00
$178.00
2
(1)

Targets VEGFR, PDGFR, and c-kit, which if related, could indirectly influence Sad-1.