Sad-1, identified predominantly in the model organism Caenorhabditis elegans, is implicated in various neuronal processes, including synaptic transmission and development. Within the intricacies of the neural system, maintaining proper synaptic function is imperative to ensure efficient communication between nerve cells. Synaptic transmission is facilitated when an electrical impulse or action potential reaches the synapse's end, leading to the release of neurotransmitters. These chemical messengers traverse the synaptic cleft and bind to receptors on the adjacent neuron, thus transmitting the signal. Proteins like Sad-1 are essential in ensuring that synapses form correctly and function properly, allowing for the precise transmission of signals across neurons.
Sad-1 Inhibitors encompass a class of compounds meticulously designed to target and impede the Sad-1 protein's function. The modulation of Sad-1 by these inhibitors can profoundly influence synaptic development and transmission. If the activity of Sad-1 is compromised by these inhibitors, it might result in aberrant synaptic connections or altered synaptic function, leading to disruptions in the communication pathways of the neural network where Sad-1 is operative. Grasping the dynamics of Sad-1 inhibitors can shed light on the multifaceted processes underpinning synaptic formation and function. A thorough exploration into the impacts of these inhibitors can offer deep insights into the regulatory mechanisms that orchestrate the harmonious and efficient transmission of signals in the nervous system, highlighting the pivotal role of proteins like Sad-1 in the grand scheme of neuronal communication.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A broad-spectrum kinase inhibitor that might influence the kinase activity of Sad-1. | ||||||
K-252a | 99533-80-9 | sc-200517 sc-200517B sc-200517A | 100 µg 500 µg 1 mg | $126.00 $210.00 $488.00 | 19 | |
Related to staurosporine, this inhibitor targets a variety of kinases and could potentially affect Sad-1. | ||||||
Lavendustin A | 125697-92-9 | sc-200539 sc-200539A | 1 mg 5 mg | $116.00 $456.00 | ||
A tyrosine kinase inhibitor that might interact with the tyrosine kinase domain of Sad-1, if present. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
A selective inhibitor of MEK, which is upstream of MAPK/ERK signaling, could indirectly influence Sad-1. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
A multi-target kinase inhibitor that may interact with kinases related to Sad-1. | ||||||
Sunitinib, Free Base | 557795-19-4 | sc-396319 sc-396319A | 500 mg 5 g | $150.00 $920.00 | 5 | |
Known to target multiple receptor tyrosine kinases, it could potentially influence Sad-1. | ||||||
Imatinib mesylate | 220127-57-1 | sc-202180 sc-202180A | 25 mg 100 mg | $44.00 $109.00 | 61 | |
As a tyrosine kinase inhibitor, it might affect tyrosine kinase domains in Sad-1. | ||||||
Vandetanib | 443913-73-3 | sc-220364 sc-220364A | 5 mg 50 mg | $167.00 $1353.00 | ||
Targets EGFR and VEGFR signaling. If Sad-1 is related to these pathways, it might be influenced. | ||||||
Nilotinib | 641571-10-0 | sc-202245 sc-202245A | 10 mg 25 mg | $205.00 $405.00 | 9 | |
Another tyrosine kinase inhibitor that might interact with kinase domains in Sad-1. | ||||||
Pazopanib | 444731-52-6 | sc-396318 sc-396318A | 25 mg 50 mg | $127.00 $178.00 | 2 | |
Targets VEGFR, PDGFR, and c-kit, which if related, could indirectly influence Sad-1. |