Rpp30 Inhibitors
Rpp30 Inhibitors are primarily designed around the modulation of RNA synthesis, processing, and maturation. Rpp30 plays a pivotal role in tRNA maturation, and its function can be modulated by influencing the broader processes and pathways of RNA metabolism. Chemicals such as α-amanitin and Actinomycin D halt RNA synthesis, thereby potentially affecting the abundance and dynamics of RNA substrates that Rpp30 acts upon.
On the other hand, nucleoside analogs like Cordycepin and Toyocamycin mimic native nucleotides but come with an inhibitory punch. Their inclusion during RNA synthesis can disrupt normal RNA metabolism, indirectly modulating the processes Rpp30 is engaged in. Similarly, compounds affecting splicing, like Spliceostatin A and Pladienolide B, can shape the landscape of RNA processing and indirectly influence the operations in which Rpp30 participates.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
RNA polymerase II inhibitor that halts mRNA synthesis, which can indirectly affect downstream RNA processing involving Rpp30. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Intercalates DNA and inhibits RNA synthesis. By decreasing the availability of RNA substrates, it can influence processes involving Rpp30. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $101.00 | 5 | |
Analog of adenosine, inhibiting RNA synthesis. This reduction in RNA synthesis can indirectly influence Rpp30's role in tRNA maturation. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
Inhibits RNA polymerase II, leading to decreased RNA synthesis. This can influence Rpp30's function by limiting available RNA substrates. | ||||||
Toyocamycin | 606-58-6 | sc-362812 | 10 mg | $138.00 | ||
Adenosine analog that inhibits certain RNA polymerases, potentially impacting RNA availability and processes involving Rpp30. | ||||||
Tubercidin | 69-33-0 | sc-258322 sc-258322A sc-258322B | 10 mg 50 mg 250 mg | $184.00 $663.00 $1958.00 | ||
Adenosine analog, inhibiting RNA synthesis and thereby potentially influencing Rpp30's role in tRNA maturation. | ||||||
8-Azaguanine | 134-58-7 | sc-207194 sc-207194A | 1 g 5 g | $84.00 $212.00 | 1 | |
Purine analog affecting RNA synthesis. By altering RNA availability, it can indirectly influence processes that Rpp30 is involved in. | ||||||
6-Thioguanine | 154-42-7 | sc-205587 sc-205587A | 250 mg 500 mg | $42.00 $54.00 | 3 | |
Purine analog which can modify RNA synthesis dynamics and thereby affect downstream processing involving Rpp30. | ||||||
Flavopiridol Hydrochloride | 131740-09-5 | sc-207687 | 10 mg | $317.00 | ||
Cyclin-dependent kinase inhibitor that can indirectly modulate RNA synthesis, influencing Rpp30-related tRNA processing. | ||||||
Spliceostatin A | 391611-36-2 | sc-507481 | 1 mg | $1800.00 | ||
Inhibits splicing by binding SF3b complex. By modulating RNA splicing, it can indirectly impact RNA processing pathways involving Rpp30. | ||||||