Rosbin activators belong to a chemical class designed to interact with and modulate the activity of the Rosbin protein. Rosbin, also known as Round spermatid basic protein 1, is a relatively novel protein that has garnered interest for its potential roles in cellular processes, particularly in male germ cell development and spermatogenesis. Research on Rosbin is still in its infancy, but early studies suggest its involvement in critical events during spermatogenesis, including chromatin remodeling, nuclear condensation, and sperm maturation. The designation activators suggests that compounds within this class interact with Rosbin to influence its activity, potentially leading to downstream effects on germ cell development and reproductive biology.
Investigations into Rosbin activators involve understanding the molecular mechanisms underlying their interaction with the Rosbin protein and how this interaction impacts cellular processes related to spermatogenesis. Elucidating the pharmacological properties of these compounds is essential for deciphering how they affect Rosbin activity and potentially influence male germ cell development. By unraveling the biological functions and regulatory mechanisms of Rosbin, researchers aim to deepen our understanding of reproductive biology and may uncover novel insights into the molecular pathways underlying spermatogenesis. Continued exploration of Rosbin activators holds promise for advancing our knowledge of male fertility and may provide insights into new strategies for manipulating germ cell development in experimental contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $30.00 $60.00 $93.00 | 27 | |
Can induce oxidative stress, potentially leading to the activation of signaling pathways that regulate gene expression in response to stress. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
A primary female sex hormone that can regulate gene expression through estrogen receptors, potentially influencing a wide array of genes. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
A synthetic glucocorticoid that can affect gene expression through glucocorticoid receptors, possibly impacting genes involved in stress responses. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
A metabolite of vitamin A that regulates gene expression through retinoic acid receptors, potentially affecting genes involved in cell differentiation and growth. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Elevates cAMP levels, which can activate PKA and potentially CREB, leading to changes in the expression of various genes. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
A histone deacetylase inhibitor that can lead to chromatin remodeling and potentially affect the expression of various genes by making their promoter regions more accessible. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
The major catechin in green tea, known for its antioxidant properties, could influence gene expression related to oxidative stress. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor affecting cell growth, proliferation, and autophagy, which could influence the expression of various genes. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Activates Nrf2, a key regulator of the antioxidant response, potentially affecting the expression of genes involved in cellular defense mechanisms. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Known for its anti-inflammatory properties, curcumin may modulate various signaling pathways, potentially affecting gene expression. | ||||||